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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease

Phase 3
Completed
Conditions
Alzheimer's Disease
Interventions
Drug: Placebo
First Posted Date
2010-10-19
Last Posted Date
2021-12-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
799
Registration Number
NCT01224106
Locations
🇺🇸

Butler Hospital, Providence, Rhode Island, United States

🇧🇷

Hospital Mae de Deus, Porto Alegre, RS, Brazil

🇩🇰

Rigshospitalet, Hukommelsesklinikken, Koebenhavn Oe, Denmark

and more 136 locations

An Observational Study on the Safety Profile of MabThera/Rituxan (Rituximab) in Combination With Chemotherapy in Patients With B Cell-lineage Chronic Lymphocytic Leukaemia (MABERYC)

Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2010-10-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
219
Registration Number
NCT01224093

An Observational Study of Herceptin (Trastuzumab) in Patients With HER2-positive Advanced Gastric Cancer

Completed
Conditions
Gastric Cancer
First Posted Date
2010-10-14
Last Posted Date
2018-06-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
443
Registration Number
NCT01220934
Locations
🇩🇪

Krankenhaus Nordwest; Klinik f. Onkologie und Hämatologie, Frankfurt, Germany

A Study of Danoprevir Boosted With Low Dose Ritonavir in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C Virus Infection

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2010-10-14
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
421
Registration Number
NCT01220947

A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-10-13
Last Posted Date
2015-01-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT01219933

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Breast Cancer

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2010-10-06
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT01215123

A Study of RoActemra/Actemra (Tocilizumab) Plus DMARDs in Patients With Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-10-05
Last Posted Date
2015-12-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01214733

A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer

Phase 3
Completed
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2010-10-05
Last Posted Date
2014-08-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
607
Registration Number
NCT01214720

An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) in Patients With Chronic Kidney Disease on Dialysis (HORTENSIA)

Completed
Conditions
Anemia
First Posted Date
2010-10-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
419
Registration Number
NCT01213485

Study of ANA773 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) to Assess Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)

Phase 1
Completed
Conditions
HCV Infection
Interventions
Drug: Placebo
First Posted Date
2010-09-29
Last Posted Date
2012-11-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
75
Registration Number
NCT01211626
Locations
🇳🇱

Erasmus MC (EMC), Rotterdam, Netherlands

🇳🇱

Academisch Medisch Centrum (AMC), Amsterdam, Netherlands

🇳🇱

PRA Clinical Research Unit, Groningen, Netherlands

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