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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-09-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01196065

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Anti-TNF Therapy (REPEAT)

Terminated
Conditions
Rheumatoid Arthritis
First Posted Date
2010-09-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1240
Registration Number
NCT01196780

A Study of Tarceva (Erlotinib) in Elderly Patients With Advanced Non-Small Cell Lung Cancer

Phase 4
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-09-08
Last Posted Date
2015-07-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
114
Registration Number
NCT01196078

A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-09-06
Last Posted Date
2014-11-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
21
Registration Number
NCT01195272

A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Phase 3
Completed
Conditions
Multiple Sclerosis, Primary Progressive
Interventions
Other: Placebo
First Posted Date
2010-09-03
Last Posted Date
2024-01-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
735
Registration Number
NCT01194570
Locations
🇺🇸

Maxine Mesinger MS Clinic/Baylor College of Medicine; Neurology, Houston, Texas, United States

🇺🇸

Swedish Neuroscience Institute; Multiple Sclerosis Center, Seattle, Washington, United States

🇺🇸

MidAmerica Neuroscience Institute, Prairie Village, Kansas, United States

and more 181 locations

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: placebo to tocilizumab IV
Drug: placebo to tocilizumab SC
Drug: Disease-modifying antirheumatic drugs (DMARDs)
First Posted Date
2010-09-03
Last Posted Date
2016-06-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1262
Registration Number
NCT01194414

An Observational Study on Long-Term Effectiveness and Safety of RoActemra/Actemra (Tocilizumab) in Daily Practice in Patients With Rheumatoid Arthritis (ICHIBAN)

Conditions
Rheumatoid Arthritis
First Posted Date
2010-09-03
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3404
Registration Number
NCT01194401

A Study of Methoxy Polyethylene Glycol-epoetin Beta (Mircera) in Participants With Chronic Kidney Disease (PRIMAVERA)

Phase 2
Completed
Conditions
Kidney Disease, Chronic
Interventions
First Posted Date
2010-09-02
Last Posted Date
2017-05-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
241
Registration Number
NCT01194154
Locations
🇩🇪

Klinikum d.Universität München Campus Großhadern, München, Germany

🇩🇪

Nierenzentrum Bogenhausen/Perlach; Praxis für Nierenheilkunde, München-Bogenhausen, Germany

🇩🇪

Charité - Klinikum Mitte; Medizinische Klinik Für Nephrologie, Berlin, Germany

and more 30 locations

An Observational Study of Tarceva (Erlotinib) in Routine Practice For First Line Maintenance Therapy in Patients With Non Small Cell Lung Cancer

Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
First Posted Date
2010-09-02
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
289
Registration Number
NCT01194050

A Study of RO4917838 (Bitopertin) in Patients With Persistent, Predominant Negative Symptoms of Schizophrenia (WN25309)

Phase 3
Completed
Conditions
Schizophrenia
Interventions
First Posted Date
2010-09-01
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
624
Registration Number
NCT01192906
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