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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study to Evaluate Efficacy and Safety of Bitopertin in Participants With Persistent, Predominant Negative Symptoms of Schizophrenia

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
Drug: Antipsychotics
First Posted Date
2010-09-01
Last Posted Date
2017-02-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
625
Registration Number
NCT01192880
Locations
🇺🇸

Synergy Clinical Research of Escondido, Escondido, California, United States

🇺🇸

Excell Research, Oceanside, California, United States

🇺🇸

Behavioral Clinical Research Inc., Lauderhill, Florida, United States

and more 100 locations

A Study of RO4917838 in Participants With Persistent, Predominant Negative Symptoms of Schizophrenia (NN25310)

Phase 3
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
Drug: Antipshychotics (Standard of Care)
First Posted Date
2010-09-01
Last Posted Date
2017-06-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
629
Registration Number
NCT01192867
Locations
🇺🇸

Family Psychiatry of the Woodlands P.A., The Woodlands, Texas, United States

🇺🇸

CNRI - Los Angeles, LLC, Pico Rivera, California, United States

🇺🇸

Pillar Clinical Research LLC, Dallas, Texas, United States

and more 119 locations

A Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) for the Treatment of Chronic Renal Anemia in Participants With Diabetic Nephropathy

Phase 4
Completed
Conditions
Anemia
Interventions
Drug: Methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2010-08-31
Last Posted Date
2018-07-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
102
Registration Number
NCT01191983
Locations
🇮🇳

Osmania General Hospital; Department of Nephrology, Hyderabad, Andhra Pradesh, India

🇮🇳

North Delhi Diabetes Centre, Delhi, India

🇮🇳

MAX Balaji Hospital, Delhi, India

and more 11 locations

A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-08-25
Last Posted Date
2012-05-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
44
Registration Number
NCT01188317

A Study of Aleglitazar in Combination With Aspirin in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-08-25
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
44
Registration Number
NCT01188304

An Observational Study of the Mean Duration of Trastuzumab (Herceptin) Treatment in Participants With Early or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer

Terminated
Conditions
Breast Cancer
Interventions
First Posted Date
2010-08-24
Last Posted Date
2017-10-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
250
Registration Number
NCT01187381
Locations
🇷🇴

Cluj Clinical County Hospital; Oncology Dept, Cluj-Napoca, Romania

A Study of RO5083945 in Combination With Chemotherapy Versus Chemotherapy Alone in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-08-20
Last Posted Date
2016-01-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT01185847

A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1

Phase 1
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
Drug: placebo
First Posted Date
2010-08-20
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
59
Registration Number
NCT01185860

An Observational Study of the Impact of RoActemra/Actemra on Fatigue in Patients With Rheumatoid Arthritis (PEPS)

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2010-08-20
Last Posted Date
2016-06-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
719
Registration Number
NCT01185522

A Study of Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-08-20
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
81
Registration Number
NCT01185873
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