MedPath

Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy

Phase 3
Terminated
Conditions
Spondylitis, Ankylosing
Interventions
Drug: Placebo
First Posted Date
2010-09-27
Last Posted Date
2013-01-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
113
Registration Number
NCT01209689

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Ankylosing Spondylitis Who Have Failed Treatment With NSAIDs

Phase 3
Terminated
Conditions
Spondylitis, Ankylosing
Interventions
Drug: Placebo
Biological: tocilizumab
First Posted Date
2010-09-27
Last Posted Date
2013-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
306
Registration Number
NCT01209702

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo - MAD
Drug: RO5271983 - SAD
Drug: Placebo - SAD
Drug: RO5271983 - MAD
First Posted Date
2010-09-27
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
82
Registration Number
NCT01209221

A Study of Erlotinib [Tarceva] as Monotherapy or Intermittent Dosing With Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer. (TALISMAN)

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-09-17
Last Posted Date
2015-11-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
74
Registration Number
NCT01204697

A Study of Rituximab (MabThera) Subcutaneous (SC) Versus Rituximab (MabThera) Intravenous in Participannts With Follicular Non-Hodgkin's Lymphoma

Phase 3
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2010-09-14
Last Posted Date
2018-11-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
410
Registration Number
NCT01200758
Locations
🇨🇴

Fundacion Cardioinfantil, Bogota, Colombia

🇲🇽

Centro Estatal De Cancerologia De Chihuahua; Servicio De Hematologia Banco De Sangre, Chihuahua, Mexico

🇨🇴

Centro Medico Imbanaco, Cali, Colombia

and more 149 locations

A Study of Bevacizumab in Combination With Gemcitabine and Carboplatin in Participants With Triple Negative Metastatic Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2010-09-14
Last Posted Date
2016-05-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT01201265

An Observational Study on The Impact of Insulin Resistance on Sustained Virological Response in Patients With Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)

Completed
Conditions
Hepatitis C, Chronic
First Posted Date
2010-09-13
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1155
Registration Number
NCT01200225

A Study of RO5310074 in Patients With Psoriatic Arthritis

Phase 1
Completed
Conditions
Arthritis, Psoriatic
Interventions
Drug: Placebo
First Posted Date
2010-09-13
Last Posted Date
2016-10-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT01199809

A Study of The Effect of Hepatic Impairment on The Pharmacokinetics of Aleglitazar

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-09-09
Last Posted Date
2015-12-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
38
Registration Number
NCT01197911

A Study of Trastuzumab Emtansine (T-DM1) Sequentially With Anthracycline-based Chemotherapy, as Adjuvant or Neoadjuvant Therapy for Patients With Early Stage Herceptin (HER)2-positive Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2010-09-08
Last Posted Date
2014-10-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
153
Registration Number
NCT01196052
© Copyright 2025. All Rights Reserved by MedPath