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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study on Infusion-related Adverse Events at Administration of MabThera (Rituximab) in Patients With Chronic Lymphocytic Leukemia

Completed
Conditions
Lymphocytic Leukemia, Chronic
Interventions
First Posted Date
2010-02-22
Last Posted Date
2016-11-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
92
Registration Number
NCT01072240

An Observational Study on the Safety and Effectiveness of Rituximab in Patients With Severe Active Rheumatoid Arthritis

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-02-19
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1653
Registration Number
NCT01071798

An Exploratory Study of RO4929097 in Patients With Recurrent or Refractory Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-02-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
7
Registration Number
NCT01070927

PROPHESYS 1: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Virus (HCV)Treated With Pegasys (Peginterferon Alfa-2a)

Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peginterferon alfa-2a (Pegasys®)
First Posted Date
2010-02-18
Last Posted Date
2016-06-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
4680
Registration Number
NCT01070550

A Study of Avastin (Bevacizumab) in Combination With Fotemustine in Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2010-02-17
Last Posted Date
2018-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01069627

A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia

Phase 4
Terminated
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2010-02-10
Last Posted Date
2017-11-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
33
Registration Number
NCT01066000
Locations
🇮🇩

Advent Hospital; Kidney and Hipertension, Bandung, Indonesia

🇮🇩

Sanglah Hospital; Kidney and Hipertension, Denpasar, Indonesia

🇮🇩

Rumah Sakit Pgi Cikini; Renal & Hypertension, Jakarta, Indonesia

and more 9 locations

A Study of First or Second Line Treatment With Tarceva (Erlotinib) in Patients With Advanced Non-Small Cell Lung Cancer

Phase 4
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2010-02-10
Last Posted Date
2016-08-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
5
Registration Number
NCT01066884

PROPHESYS 3: Observational Study on Predictors of Response in Patients With Treatment-naïve Chronic Hepatitis C Initiated on Treatment With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peginterferon alfa-2a [Pegasys]
Drug: Peginterferon alfa-2b [PegIntron®]
First Posted Date
2010-02-10
Last Posted Date
2016-08-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1656
Registration Number
NCT01066819

PROPHESYS 2: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peginterferon alfa-2a [Pegasys]
Drug: Peginterferon alfa-2b [PegIntron®]
First Posted Date
2010-02-10
Last Posted Date
2016-05-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2343
Registration Number
NCT01066793

PRM-151 in the Prevention of Scarring Following Trabeculectomy

Phase 2
Completed
Conditions
Glaucoma
Interventions
Drug: Placebo
First Posted Date
2010-02-08
Last Posted Date
2022-04-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
124
Registration Number
NCT01064817
Locations
🇳🇱

UMC St. Radboud West, Nijmegen, Netherlands

🇬🇧

Oxford Eye Hosiptal, Oxford, United Kingdom

🇬🇧

St. Thomas, London, United Kingdom

and more 11 locations
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