MedPath

Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-05-10
Last Posted Date
2013-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
326
Registration Number
NCT01119859

A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas

Phase 2
Completed
Conditions
Brainstem Glioma
Interventions
Radiation: Radiation therapy
First Posted Date
2010-05-06
Last Posted Date
2014-02-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT01118377

A Study of the Effect of RO4917838 on Biomarker Measures of Cognitive Dysfunction in Participants With Schizophrenia and Schizoaffective Disorder

Phase 1
Completed
Conditions
Schizophrenia
Interventions
Drug: Placebo
Drug: Standard Antipsychotic Therapy
First Posted Date
2010-05-05
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
29
Registration Number
NCT01116830

A Study of Efficacy of Rituximab [Mabthera/Rituxan] in Patients With Rheumatoid Arthritis Using Magnetic Resonance Imaging of the Hand (RESONAR)

Phase 4
Terminated
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-05-05
Last Posted Date
2014-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
2
Registration Number
NCT01117129

A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme

Phase 2
Completed
Conditions
Glioblastoma Multiforme
Interventions
First Posted Date
2010-05-04
Last Posted Date
2014-12-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
32
Registration Number
NCT01115491

A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic Melanoma

Phase 1
Completed
Conditions
Malignant Melanoma
Interventions
First Posted Date
2010-04-21
Last Posted Date
2015-08-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT01107418

An Observational Study of Epoetin Beta [Neorecormon] to Evaluate the Quality of Life in Patients on Dialysis With Chronic Renal Anemia

Completed
Conditions
Anemia
First Posted Date
2010-04-16
Last Posted Date
2012-09-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6000
Registration Number
NCT01105494

A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-04-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT01099904

A Study of Balapiravir in Patients With Dengue Virus Infection

Phase 1
Completed
Conditions
Dengue
Interventions
First Posted Date
2010-03-31
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
64
Registration Number
NCT01096576

A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV)

Phase 3
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: Pegylated interferon (PEG-IFN) alfa-2a, 180 mcg
Drug: Pegylated interferon (PEG-IFN) alfa-2a, 135 mcg
First Posted Date
2010-03-30
Last Posted Date
2016-11-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
131
Registration Number
NCT01095835
© Copyright 2025. All Rights Reserved by MedPath