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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of RO5212054 (PLX3603) in Participants With BRAF V600-Mutated Advanced Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2010-06-14
Last Posted Date
2017-07-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT01143753
Locations
🇦🇺

Royal Adelaide Hospital; Oncology, Adelaide, South Australia, Australia

🇪🇸

Hospital Univ Vall d'Hebron; Servicio de Oncologia, Barcelona, Spain

🇩🇰

Rigshospitalet, Onkologisk Klinik, København Ø, Denmark

and more 2 locations

A Study of RO5045337 in Patients With Liposarcomas Prior to Debulking Surgery

Phase 1
Completed
Conditions
Sarcoma
Interventions
First Posted Date
2010-06-14
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT01143740

A Study of Bevacizumab Added to Trastuzumab Plus Docetaxel in the Neoadjuvant Setting in Participants With Early Stage HER2-Positive Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
Procedure: Surgery
Radiation: Radiotherapy
Drug: Hormonal Therapy
First Posted Date
2010-06-11
Last Posted Date
2018-03-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
152
Registration Number
NCT01142778
Locations
🇫🇷

Centre Leon Berard; Oncologie Genetique, Lyon, France

🇫🇷

Centre D'Oncologie de Gentilly; Oncology, Nancy, France

🇫🇷

Centre Radiotherapie Marie Curie, Arras, France

and more 25 locations

A Study of Avastin (Bevacizumab) in Combination With Xelox and Tarceva in Patients With Metastatic Colorectal Cancer.

First Posted Date
2010-06-02
Last Posted Date
2015-02-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT01135498

Accu-Chek missiOn: SMBG in Patients With diAbetes on inSulin Study (COMPASS) - Multiple Center, Open, and Non-randomized Study

Not Applicable
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Device: Accu-Chek Integra Glucometer
First Posted Date
2010-05-26
Last Posted Date
2017-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
833
Registration Number
NCT01130480

A Study of Capecitabine [Xeloda] in Combination With Trastuzumab [Herceptin] and Oxaliplatine in Patients With Resectable Gastric Cancer

Phase 2
Completed
Conditions
Gastric Cancer
Interventions
First Posted Date
2010-05-26
Last Posted Date
2015-10-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
36
Registration Number
NCT01130337

A Study of Avastin (Bevacizumab) in Combination Chemotherapy in Patients With Metastatic Cancer of the Colon or Rectum

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2010-05-26
Last Posted Date
2015-06-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
306
Registration Number
NCT01131078

A Study of Ibandronate [Bonviva/Boniva] and Alendronate in Female Patients With Post-Menopausal Osteoporosis

Completed
Conditions
Postmenopausal Osteoporosis
Interventions
First Posted Date
2010-05-21
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
6054
Registration Number
NCT01128257

SMART Study: A Study of Re-treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on Anti-TNF Alfa Therapy

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-05-19
Last Posted Date
2014-09-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
224
Registration Number
NCT01126541

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-05-10
Last Posted Date
2013-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
326
Registration Number
NCT01119859
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