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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Monthly Subcutaneous or Intravenous Mircera in Dialysis Patients With Chronic Renal Anaemia

Phase 4
Completed
Conditions
Anemia
Interventions
Procedure: Dialysis
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2010-07-02
Last Posted Date
2015-12-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
86
Registration Number
NCT01156363

A Study of Induction and Maintenance Treatment With MabThera (Rituximab) in Patients With Indolent B-Cell Nonfollicular Lymphomas

Phase 2
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2010-06-30
Last Posted Date
2017-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
47
Registration Number
NCT01153971
Locations
🇮🇹

Universita' Degli Studi La Sapienza-Ist.Di Ematologia;Dip. Biotecnologie Cel CELLULARI ED EMATOLOGIA, Roma, Lazio, Italy

🇮🇹

Ospedale Civile; Divisione Di Oncologia, Pescara, Abruzzo, Italy

🇮🇹

A.O.U. Policlinico di Modena-Dipartimento di Medicina Diagnostica, Clinica e di Sanità pubblica, Modena, Emilia-Romagna, Italy

and more 12 locations

A Study to Assess Biomarkers Impact on Participants Response to Erlotinib Treatment for First-line Non-Small Cell Lung Cancer With Endothelial Growth Factor Receptor (EGFR) Activating Mutations

Phase 2
Completed
Conditions
Carcinoma,Non-Small-Cell Lung
Interventions
First Posted Date
2010-06-30
Last Posted Date
2017-04-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT01153984
Locations
🇷🇴

Spitalul de Boli Cronice Sf. Luca, Bucharest, Romania

🇷🇴

Emergency University Bucharest Hospital; Oncology Department, Bucharest, Romania

🇷🇴

ONCOMED - Medical Centre, Timisoara, Romania

and more 6 locations

A Study of RO5024048 in Japanese and Caucasian Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2010-06-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
97
Registration Number
NCT01152671

A Study of Cardiac Safety in Patients With HER2 Positive Early Breast Cancer Treated With Herceptin

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2010-06-29
Last Posted Date
2018-01-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3942
Registration Number
NCT01152606
Locations
🇦🇹

Lkh-Univ. Klinikum Graz; Klinik Für Gynäkologie, Graz, Austria

🇦🇹

LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie, Graz, Austria

🇦🇹

LKH Hochsteiermark; Abt. für Innere Medizin, Leoben, Austria

and more 202 locations

A Study of RO4989991 in Patients With Allergic Rhinitis

Phase 1
Completed
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2010-06-29
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT01152619

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic and/or Biologic DMARDS

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2010-06-23
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
145
Registration Number
NCT01149057

A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer

Phase 1
Completed
Conditions
Colorectal Cancer, Ovarian Cancer
Interventions
First Posted Date
2010-06-22
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
7
Registration Number
NCT01148758

A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin's Lymphoma (NHL)

Phase 3
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2010-06-15
Last Posted Date
2017-08-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
234
Registration Number
NCT01144364
Locations
🇮🇹

Dept. Medicina Clinica E Sperimentale; Sez. Medicina Interna E Scienze Oncologiche - Pol. Monteluce, Perugia, Umbria, Italy

🇮🇹

ASST PAPA GIOVANNI XXIII; Ematologia, Bergamo, Lombardia, Italy

🇮🇹

Ospedale S. Eugenio; Divisione Di Ematologia, Roma, Lazio, Italy

and more 42 locations

A Study of MabThera (Rituximab) Addition to Regularly Prescribed Chemotherapy in Patients With Untreated Mantle Cell Lymphoma.

Phase 2
Terminated
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
First Posted Date
2010-06-15
Last Posted Date
2016-10-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT01144403
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