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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of the Ability of Functional Magnetic Resonance Imaging (fMRI) to Detect and Characterize the Effects of Two Marketed Centrally Active Drugs, Placebo, and RO4917523 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
First Posted Date
2010-01-08
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
25
Registration Number
NCT01045083

A Study of Tocilizumab in Combination With an Oral Contraceptive in Patients With Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Ortho-Novum® 1/35
First Posted Date
2010-01-08
Last Posted Date
2013-04-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
46
Registration Number
NCT01044498

A Study of Single Doses of RO4998452 in Patients With Type 2 Diabetes

Phase 1
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2010-01-07
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT01044017

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Phase 3
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Drug: Placebo
First Posted Date
2010-01-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
7226
Registration Number
NCT01042769

A Study of Aleglitazar in Type 2 Diabetes Patients With Moderate Renal Impairment

Phase 2
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
First Posted Date
2010-01-06
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
302
Registration Number
NCT01043029

ToGA Study - A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer

Phase 3
Completed
Conditions
Gastric Cancer
Interventions
First Posted Date
2009-12-31
Last Posted Date
2014-11-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
584
Registration Number
NCT01041404

A Study of Tocilizumab Plus Non-biological DMARD in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Non-biological DMARDs

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: placebo
Drug: non-biological DMARDs
First Posted Date
2009-12-17
Last Posted Date
2018-03-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
54
Registration Number
NCT01034397

A Pharmacokinetic Study of CellCept (Mycophenolate Mofetil) Versus Mycophenolate Sodium in Kidney Transplant Patients

Phase 4
Completed
Conditions
Kidney Transplantation
Interventions
First Posted Date
2009-12-17
Last Posted Date
2015-08-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
23
Registration Number
NCT01033864

A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2009-12-17
Last Posted Date
2016-07-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
317
Registration Number
NCT01034137

A Study of Extended Therapy of PEGASYS (Peginterferon Alfa-2a) in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C and Slow Response

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2009-12-16
Last Posted Date
2017-10-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
59
Registration Number
NCT01033448
Locations
🇮🇱

Holy Family Medical Center; Gastroenterology, Nazareth, Israel

🇮🇱

Haemek Hospital; Gastroenterology, Afula, Israel

🇮🇱

Clalit City Ashdod MC; Liver Clinic, Ashdod, Israel

and more 17 locations
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