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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Avastin (Bevacizumab) Plus Herceptin (Trastuzumab) in Patients With Primary Inflammatory HER2-Positive Breast Cancer.

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2008-07-17
Last Posted Date
2016-08-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT00717405

Study to Determine Optimum Intravenous Starting Dose of MIRCERA for Treatment of Pediatric Participants With Anemia and Chronic Kidney Disease on Hemodialysis

Phase 2
Completed
Conditions
Renal Anemia
Interventions
First Posted Date
2008-07-17
Last Posted Date
2017-09-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
64
Registration Number
NCT00717366
Locations
🇪🇸

Hospital Universitario La Paz: Nefrologia Pediatrica, Madrid, Spain

🇮🇹

IRCCS G. Gaslini; U.O. Nefrologia, Dialisi e Trapianto, Genova, Liguria, Italy

🇪🇸

Hospital Universitario la Fe; Servicio de Nefrologia Pediatrica, Valencia, Spain

and more 36 locations

A Study of CellCept (Mycophenolate Mofetil) Combined With Calcineurin Inhibitors in Liver Transplant Patients.

Phase 4
Completed
Conditions
Liver Transplantation
Interventions
Drug: CNI (50%)
Drug: CNI (≥75%)
First Posted Date
2008-07-17
Last Posted Date
2014-09-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
87
Registration Number
NCT00717314

A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas

Phase 1
Completed
Conditions
Pancreatic Neoplasm
Interventions
Biological: monoclonal antibody
Drug: chemotherapy
First Posted Date
2008-07-08
Last Posted Date
2013-12-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT00711191
Locations
🇺🇸

Pfizer Investigational Site, Philadelphia, Pennsylvania, United States

Evaluation of the Cobas® 4800 HPV Test for the Detection of High-grade Cervical Disease

Not Applicable
Completed
Conditions
Human Papilloma Virus (HPV)
Interventions
Device: cobas® 4800 HPV Test
First Posted Date
2008-07-03
Last Posted Date
2015-02-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
47208
Registration Number
NCT00709891

A Study of First Line Treatment With Tarceva (Erlotinib) in Combination With Gemcitabine in Patients With Unresectable Advanced and/or Metastatic Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-small Cell Lung Cancer Metastatic
Interventions
First Posted Date
2008-06-19
Last Posted Date
2016-06-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT00701558

A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Colorectal Cancer

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2008-06-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT00700570

A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer.

Phase 3
Completed
Conditions
Colorectal Cancer
Interventions
Drug: Chemotherapy
First Posted Date
2008-06-18
Last Posted Date
2015-07-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
820
Registration Number
NCT00700102

A Study of Avastin (Bevacizumab) in Combination With Carboplatin-Based Chemotherapy in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer.

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
Drug: Carboplatin-based chemotherapy
First Posted Date
2008-06-18
Last Posted Date
2014-09-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
303
Registration Number
NCT00700180

A Study of Monthly Intravenous C.E.R.A. (Mircera) in Hemodialysis Participants With Chronic Renal Anemia

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: Methoxy polyethylene glycol-epoetin beta (C.E.R.A.)
First Posted Date
2008-06-18
Last Posted Date
2016-04-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
351
Registration Number
NCT00699348
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