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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Prophylactic Treatment for Hand-Foot Syndrome in Patients Treated With Oral Xeloda (Capecitabine).

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2008-04-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
598
Registration Number
NCT00661102

ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B

Phase 3
Completed
Conditions
Hepatitis B, Chronic
Interventions
Drug: peginterferon alfa-2a [Pegasys]
First Posted Date
2008-04-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
10
Registration Number
NCT00661076

A Study of Monthly Subcutaneous Mircera for the Treatment of Chronic Renal Anemia in Predialysis Patients Not Treated With ESA.

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2008-04-18
Last Posted Date
2016-08-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
75
Registration Number
NCT00661388

A Study of Intravenous Mircera in Hemodialysis Patients With Chronic Renal Anemia

Phase 3
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-04-18
Last Posted Date
2017-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
132
Registration Number
NCT00661505
Locations
🇹🇷

Adnan Menderes Uni School of Medicine; Physical Therapy & Rehabilitation, Aydin, Turkey

🇹🇷

Trakya University Medical Faculty; Internal Medicine; Nephrology, Edirne, Turkey

🇹🇷

Izmir Ataturk Research and Training Hospital; The Clinic of Nephrology, Izmir, Turkey

and more 17 locations

A Study of Avastin (Bevacizumab) in Combination With Docetaxel and Cisplatin in Patients With Metastatic or Locally Advanced Non-small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-small Cell Lung Cancer
Interventions
First Posted Date
2008-04-18
Last Posted Date
2014-07-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
50
Registration Number
NCT00661778

A Study of Intravenous Mircera in Participants With Chronic Renal Anemia Who Are on Dialysis

Phase 3
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-04-17
Last Posted Date
2016-03-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
124
Registration Number
NCT00660023

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Phase 3
Completed
Conditions
Coronary Heart Disease
Interventions
Drug: Evidence-based medical care for Acute Coronary Syndrome
Drug: Placebo
First Posted Date
2008-04-15
Last Posted Date
2020-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
15871
Registration Number
NCT00658515

A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients

Phase 2
Completed
Conditions
Coronary Heart Disease
Interventions
Drug: Placebo
First Posted Date
2008-04-10
Last Posted Date
2020-01-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
476
Registration Number
NCT00655538

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

Phase 2
Completed
Conditions
Coronary Heart Disease
Interventions
First Posted Date
2008-04-10
Last Posted Date
2020-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
130
Registration Number
NCT00655473

A Dose-Escalation to Rash Study of Tarceva (Erlotinib) Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer

Phase 2
Completed
Conditions
Pancreatic Cancer
Interventions
Drug: Erlotinib, escalating dose
Drug: Erlotinib, standard dose
First Posted Date
2008-04-03
Last Posted Date
2015-02-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
467
Registration Number
NCT00652366
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