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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

PRISMA Study (Prospective, Randomized Trial on Intensive Self-Monitoring Blood Glucose Management Added Value in Non-Insulin Treated Type 2 Diabetes Mellitus Patients)

Not Applicable
Completed
Conditions
Diabetes Mellitus Type 2
Interventions
Device: Accu-Chek Aviva Meter
First Posted Date
2008-03-26
Last Posted Date
2016-03-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1000
Registration Number
NCT00643474

A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.

Phase 2
Completed
Conditions
Sarcoma
Interventions
Drug: Standard chemotherapy
First Posted Date
2008-03-26
Last Posted Date
2019-10-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
154
Registration Number
NCT00643565
Locations
🇧🇪

Cliniques Universitaires St-Luc, Bruxelles, Belgium

🇧🇪

Hôpital Enfants Reine Fabiola, Bruxelles, Belgium

🇧🇪

UZ Gent, Gent, Belgium

and more 58 locations

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

Phase 3
Completed
Conditions
Juvenile Idiopathic Arthritis
Interventions
Drug: Placebo
Drug: Non-steroidal anti-inflammatory drugs (NSAIDs)
Drug: corticosteroids
First Posted Date
2008-03-25
Last Posted Date
2016-07-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
112
Registration Number
NCT00642460

A Study of Metronidazole Cream in the Prevention and Treatment of Tarceva (Erlotinib)-Associated Rash

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
Other: Non-active Moisturizing Cream
First Posted Date
2008-03-25
Last Posted Date
2016-05-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
34
Registration Number
NCT00642473

A Study of Subcutaneous C.E.R.A. for the Maintenance of Hemoglobin Levels in Participants With Chronic Renal Anemia Not on Dialysis.

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [C.E.R.A.]
First Posted Date
2008-03-25
Last Posted Date
2018-06-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT00642304
Locations
🇳🇱

Albert Schweitzer Ziekenhuis; Inwendige Geneeskunde, Dordrecht, Netherlands

🇳🇱

Nij Smellinghe Ziekenhuis; Inwendige Geneeskunde, Drachten, Netherlands

🇳🇱

Oosterscheldeziekenhuis, Goes, Netherlands

and more 20 locations

A Study of R1507 in Participants With Recurrent or Refractory Sarcoma

Phase 2
Terminated
Conditions
Sarcoma
Interventions
First Posted Date
2008-03-25
Last Posted Date
2021-02-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
317
Registration Number
NCT00642941
Locations
🇺🇸

Johns Hopkins Hospital, Baltimore, Maryland, United States

🇺🇸

UCLA School Of Medicine Mattel's Children's Hospital At UCLA; Division Of Hematology-Oncology, Los Angeles, California, United States

🇺🇸

Pennsylvania Oncology Hema Asc, Philadelphia, Pennsylvania, United States

and more 38 locations

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

First Posted Date
2008-03-25
Last Posted Date
2018-03-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
41
Registration Number
NCT00642603

A Genetic Substudy Associated With the Avastin (Bevacizumab) Study MO19390 in Patients With Advanced or Recurrent Non-Squamous Cell Lung Cancer.

Phase 2
Terminated
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
Drug: Standard chemotherapy
First Posted Date
2008-03-25
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
3
Registration Number
NCT00642824

A Study of Subcutaneous Mircera for the Maintenance Treatment of Participants With Chronic Renal Anemia

Phase 4
Completed
Conditions
Anemia
Interventions
First Posted Date
2008-03-25
Last Posted Date
2017-07-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
35
Registration Number
NCT00642668
Locations
🇧🇪

ZNA Stuivenberg, Antwerpen, Belgium

🇧🇪

ZNA Middelheim, Antwerpen, Belgium

🇧🇪

CH EpiCURA Site Hornu, Hornu, Belgium

and more 29 locations

A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer.

Phase 3
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2008-03-25
Last Posted Date
2022-12-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
214
Registration Number
NCT00642577
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