MedPath

Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Dose Finding Study Of CP-870,893, An Immune System Stimulating Antibody, In Combination With Paclitaxel And Carboplatin For Patients With Metastatic Solid Tumors

Phase 1
Completed
Conditions
Neoplasms
Interventions
First Posted Date
2008-02-05
Last Posted Date
2017-03-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
34
Registration Number
NCT00607048
Locations
🇺🇸

Pfizer Investigational Site, San Antonio, Texas, United States

A Study of Tarceva (Erlotinib) and Avastin (Bevacizumab) in Patients With Advanced or Metastatic Liver Cancer.

Phase 2
Completed
Conditions
Liver Cancer
Interventions
First Posted Date
2008-01-31
Last Posted Date
2014-07-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
51
Registration Number
NCT00605722

A Study Comparing Subcutaneous Mircera and Darbepoetin Alfa for Maintenance Treatment of Anemia in Kidney Transplant Recipients.

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2008-01-31
Last Posted Date
2016-09-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
71
Registration Number
NCT00605345

A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Placebo
Biological: Rituximab
Drug: Folic acid or folate
First Posted Date
2007-12-21
Last Posted Date
2015-04-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT00578305

A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant

Phase 4
Terminated
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
Drug: Supportive treatment
First Posted Date
2007-12-19
Last Posted Date
2016-11-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1
Registration Number
NCT00576602

A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer.

Phase 2
Withdrawn
Conditions
Colorectal Cancer
Interventions
First Posted Date
2007-12-19
Last Posted Date
2018-07-31
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT00577109

A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2007-12-19
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT00576433

GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma

Phase 2
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2007-12-19
Last Posted Date
2014-08-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
175
Registration Number
NCT00576758

A Study of Intravenous Mircera in Dialysis Patients With Chronic Renal Disease and Anemia.

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: methoxy polyethylene glycol-epoetin beta [Mircera]
First Posted Date
2007-12-19
Last Posted Date
2016-05-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
200
Registration Number
NCT00576303
© Copyright 2025. All Rights Reserved by MedPath