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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Open-Label Extension and Safety Study for Participants With Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Study GA29144

Phase 3
Terminated
Conditions
Crohn Disease
Interventions
First Posted Date
2015-03-31
Last Posted Date
2024-12-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
790
Registration Number
NCT02403323
Locations
🇭🇺

Semmelweis Egyetem; Belgyogyaszati es Hematologiai Klinika, Budapest, Hungary

🇺🇸

Valley Gastroenterology Consultants, Arcadia, California, United States

🇺🇸

University of California San Diego Medical Center, La Jolla, California, United States

and more 284 locations

Non-Interventional Study of Tocilizumab Subcutaneous (SC) Monotherapy in Participants With Rheumatoid Arthritis (RA)

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2015-03-30
Last Posted Date
2019-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
353
Registration Number
NCT02402686
Locations
🇭🇺

National Institute of Rheumatology and Physiotherapy; 4Th Rheumatology Department, Budapest, Hungary

🇭🇺

Budai Irgalmasrendi Kórház KHT. II. Reumatológia, Budapest, Hungary

🇭🇺

Szent Andras Reumakorhaz; Reumatologia, Heviz, Hungary

and more 15 locations

Phase IIIb Study to Evaluate the Safety and Tolerability of Herceptin SC With Perjeta and Docetaxel in Patients With HER2-positive Advanced Breast Cancer

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2015-03-30
Last Posted Date
2019-09-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
418
Registration Number
NCT02402712
Locations
🇵🇱

MAGODENT Sp. z o.o., Warsaw, Poland

🇫🇷

Pole Sante Republique; Pharmacie Oncologique, Clermont Ferrand, France

🇩🇪

Studienzentrum Aschaffenburg, Aschaffenburg, Germany

and more 109 locations

A Study of Disease Progression in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Terminated
Conditions
Geographic Atrophy
Interventions
Other: No intervention
First Posted Date
2015-03-26
Last Posted Date
2019-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
202
Registration Number
NCT02399072
Locations
🇺🇸

Midwest Vision Research Foundation, Chesterfield, Missouri, United States

🇺🇸

Retina Consultants of Houston, The Woodlands, Texas, United States

🇺🇸

Retina Assoc of Cleveland Inc, Cleveland, Ohio, United States

and more 60 locations

Human Epidermal Growth Factor Receptor 2 (HER2) Positive Unresectable Locally Advanced or Metastatic Breast Cancer Disease Registry Study

Completed
Conditions
Breast Cancer
Interventions
Other: No intervention
First Posted Date
2015-03-20
Last Posted Date
2024-02-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
311
Registration Number
NCT02393924
Locations
🇬🇧

Kent & Canterbury Hospital, Canterbury, United Kingdom

🇬🇧

Chesterfield Royal Hospital, Chesterfield, United Kingdom

🇬🇧

Royal Cornwall Hospital; Dept of Clinical Oncology, Cornwall, United Kingdom

and more 26 locations

BELOVA Data Collection: Safety and Efficacy of Frontline Bevacizumab Treatment in Participants With Ovarian Cancer 70 Years and Older

Completed
Conditions
Ovarian Cancer
Interventions
First Posted Date
2015-03-20
Last Posted Date
2019-07-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
76
Registration Number
NCT02393898
Locations
🇧🇪

UZ Antwerpen, Edegem, Belgium

🇧🇪

Sint Augustinus Wilrijk, Wilrijk, Belgium

🇧🇪

UZ Leuven Gasthuisberg, Leuven, Belgium

and more 23 locations

A Study to Assess Whether Etrolizumab is a Safe and Efficacious Treatment for Participants With Moderately to Severely Active Crohn's Disease

Phase 3
Completed
Conditions
Crohn Disease
Interventions
Drug: Placebo
First Posted Date
2015-03-20
Last Posted Date
2022-11-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1035
Registration Number
NCT02394028
Locations
🇺🇸

Innovative Medical Research of South Florida, Aventura, Florida, United States

🇦🇹

LKH - Universitätsklinikum der PMU Salzburg, Salzburg, Austria

🇭🇷

Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia

and more 324 locations

A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection

Phase 2
Completed
Conditions
Hepatitis B, Chronic
Interventions
First Posted Date
2015-03-18
Last Posted Date
2018-06-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
31
Registration Number
NCT02391805
Locations
🇲🇾

University Malaya Medical Center, Kuala Lumpur, Malaysia

🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

🇰🇷

Severance Hospital, Yonsei University Health System, Seoul, Korea, Republic of

and more 11 locations

A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)

First Posted Date
2015-03-09
Last Posted Date
2020-11-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
135
Registration Number
NCT02383589
Locations
🇹🇷

Gülhane Military Medical Academy in Ankara, Ankara, Turkey

🇪🇸

Hospital de la Victoria, Malaga, Spain

🇺🇦

Dnipropetrovsk State Medical Academy, Dnipropterovsk, Ukraine

and more 65 locations

Retrospective Data Collection: Post Study Treatment Anticancer Therapy From IMELDA MO22223

Completed
Conditions
Breast Cancer
Interventions
Other: No Intervention
First Posted Date
2015-03-09
Last Posted Date
2018-04-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
185
Registration Number
NCT02383576
Locations
🇪🇸

Hospital Virgen de los Lirios; Servicio de Oncologia, Alcoy, Alicante, Spain

🇪🇸

Corporacio Sanitaria Parc Tauli; Servicio de Oncologia, Sabadell, Barcelona, Spain

🇧🇷

Hospital de Caridade de Ijui; Oncologia, Ijui, RS, Brazil

and more 29 locations
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