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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Non-Interventional Study of Xeloda (Capecitabine) in Patients With Gastric Cancer

Completed
Conditions
Gastric Cancer
First Posted Date
2014-10-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
223
Registration Number
NCT02274376

A German Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Type 2 Diabetes Patients.

Not Applicable
Completed
Conditions
Diabetes Mellitus, Type 2
Interventions
Device: Accu-Chek Smart Pix readout Device
Device: Accu-Chek Smart Pix Software
First Posted Date
2014-10-20
Last Posted Date
2017-11-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
414
Registration Number
NCT02268929

Observational Study of Pertuzumab Safety in Participants With Breast Cancer

Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2014-10-16
Last Posted Date
2021-05-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1130
Registration Number
NCT02266173
Locations
🇰🇷

Inje university Haeundae Paik Hospital, Busan, Korea, Republic of

🇰🇷

Pusan National University Hospital, Busan, Korea, Republic of

🇰🇷

Kyungpook National University Chilgok Hospital, Daegu, Korea, Republic of

and more 34 locations

A Study of Pegylated Interferon Alfa-2A in Combination With Lamivudine or Entecavir Compared With Untreated Control Group in Children With Hepatitis B Envelope Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) in the Immune-Tolerant Phase

Phase 3
Completed
Conditions
Pediatric Immuno-Tolerant Chronic Hepatitis B
Interventions
First Posted Date
2014-10-13
Last Posted Date
2020-08-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
62
Registration Number
NCT02263079
Locations
🇧🇪

Cliniques Universitaires St-Luc, Bruxelles, Belgium

🇮🇹

Azienda Ospedaliero-Universitaria Policlinico S. Orsola Malpighi; U.O. Malattie Infettive, Bologna, Emilia-Romagna, Italy

🇩🇪

Universitätsklinikum Essen; Klinik für Kinder- und Jugendmedizin Pädiatrie II, Essen, Germany

and more 22 locations

An Observational, Prospective, Safety Study of Mircera (Monopegylated Epoetin Beta) in Clinical Practice

Completed
Conditions
Kidney Disease, Chronic
Interventions
First Posted Date
2014-10-13
Last Posted Date
2016-09-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
748
Registration Number
NCT02263833

A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma

Phase 1
Completed
Conditions
Lymphoma
Interventions
Drug: Polatuzumab vedotin (Liquid)
Drug: Polatuzumab vedotin (Lyophilized)
First Posted Date
2014-10-06
Last Posted Date
2022-11-14
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
331
Registration Number
NCT02257567
Locations
🇳🇱

UMC St. Radboud; Hematology, Nijmegen, Netherlands

🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

Swedish Cancer Inst., Seattle, Washington, United States

and more 59 locations

A Study of RO5186582 Treatment on Cytochrome P450 (CYP) 3A4 Activity in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Midazolam, oral
Drug: Midazolam, IV
First Posted Date
2014-10-02
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT02254759

Study of Tocilizumab (RoActemre) Administered Subcutaneously in Participants With Rheumatoid Arthritis in Everyday Clinical Practice

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2014-09-29
Last Posted Date
2020-09-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1454
Registration Number
NCT02251860
Locations
🇩🇪

CIRI - Centrum für Innovative Diagnostik und Therapie Rheumatologie/ Immunologie (GmbH), Frankfurt, Germany

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Phase 3
Terminated
Conditions
Geographic Atrophy
Interventions
First Posted Date
2014-09-25
Last Posted Date
2019-06-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
906
Registration Number
NCT02247479
Locations
🇺🇸

Texas Retina Associates, Arlington, Texas, United States

🇺🇸

Orange County Retina Med Group, Santa Ana, California, United States

🇺🇸

Maine Eye Center, Portland, Maine, United States

and more 141 locations

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Phase 3
Terminated
Conditions
Geographic Atrophy
Interventions
Other: Sham Comparator
First Posted Date
2014-09-25
Last Posted Date
2019-10-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
975
Registration Number
NCT02247531
Locations
🇺🇸

Southern Vitreoretinal Assoc, Tallahassee, Florida, United States

🇺🇸

Retina Health Center, Fort Myers, Florida, United States

🇺🇸

Retina Consultants of Orange County, Fullerton, California, United States

and more 149 locations
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