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Roche Holding AG

Roche Holding AG logo
๐Ÿ‡จ๐Ÿ‡ญSwitzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study of Continued Bevacizumab Plus Chemotherapy Until First Progression in Participants With Metastatic Colorectal Cancer (CRC)

Completed
Conditions
Colorectal Cancer
Interventions
Other: Bevacizumab
Combination Product: Chemotherapy
First Posted Date
2014-12-02
Last Posted Date
2018-08-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
300
Registration Number
NCT02305615
Locations
๐Ÿ‡ญ๐Ÿ‡บ

Debreceni Egyetem Klinikai Kozpont ; Department of Oncology, Debrecen, Hungary

๐Ÿ‡ญ๐Ÿ‡บ

Szent Margit Hospital, Budapest, Hungary

๐Ÿ‡ญ๐Ÿ‡บ

Semmelweis Egyetem Onkologiai Kรถzpont, Budapest, Hungary

and more 19 locations

A Study of Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Solid Tumors
Interventions
First Posted Date
2014-12-01
Last Posted Date
2019-12-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
140
Registration Number
NCT02304393
Locations
๐Ÿ‡ฉ๐Ÿ‡ฐ

Rigshospitalet; Onkologisk Klinik, Kรธbenhavn ร˜, Denmark

๐Ÿ‡จ๐Ÿ‡ฆ

University Health Network; Princess Margaret Hospital; Medical Oncology Dept, Toronto, Ontario, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

Jewish General Hospital / McGill University, Montreal, Quebec, Canada

and more 8 locations

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

First Posted Date
2014-11-27
Last Posted Date
2019-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
931
Registration Number
NCT02302807
Locations
๐Ÿ‡ท๐Ÿ‡ธ

Oncology Institute of Vojvodina, Sremska Kamenica, Serbia

๐Ÿ‡ฌ๐Ÿ‡ง

Barts and The London, London, United Kingdom

๐Ÿ‡จ๐Ÿ‡ฆ

Tom Baker Cancer Centre-Calgary, Calgary, Alberta, Canada

and more 214 locations

A Study of RG7625 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2014-11-20
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT02295332

A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
Drug: FOLFOX induction regimen
Drug: Fluoropyrimidine (5-FU/LV or capecitabine)
Drug: 5-FU/LV
First Posted Date
2014-11-14
Last Posted Date
2024-05-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1044
Registration Number
NCT02291289
Locations
๐Ÿ‡ฆ๐Ÿ‡ท

Hospital de Gastroenterologia Dr. Bonorino Udaondo ; Servicio de Oncologรญa, Buenos Aires, Argentina

๐Ÿ‡ง๐Ÿ‡ช

Institut Jules Bordet X, Brussels, Belgium

๐Ÿ‡ง๐Ÿ‡ช

Hospital Erasme, Bruxelles, Belgium

and more 151 locations

A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2014-11-13
Last Posted Date
2019-08-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
49
Registration Number
NCT02289833
Locations
๐Ÿ‡ต๐Ÿ‡ฑ

Medical University of Gdansk, Gdansk, Poland

๐Ÿ‡ต๐Ÿ‡ฑ

Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy; Oddzial Iii, Otwock, Poland

๐Ÿ‡จ๐Ÿ‡ญ

CHUV; Departement d'Oncologie, Lausanne, Switzerland

and more 20 locations

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer: Continued Avastin Plus Chemotherapy After First Progression in Clinical Practice

Completed
Conditions
Colorectal Cancer
First Posted Date
2014-11-10
Last Posted Date
2018-07-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT02287597
Locations
๐Ÿ‡ญ๐Ÿ‡ท

Clinical Hospital Osijek; Dept For Oncology & Radiotherapy, Osijek, Croatia

๐Ÿ‡ญ๐Ÿ‡ท

Uni Hospital Split; Oncology & Radiotherapy, Split, Croatia

๐Ÿ‡ญ๐Ÿ‡ท

Uni Hospital For Tumours; Dept of Medical Oncology, Zagreb, Croatia

and more 1 locations

An Observational Study of the Safety of Herceptin Given Subcutaneously in Patients With Early HER2-positive Breast Cancer

Completed
Conditions
Breast Cancer
First Posted Date
2014-11-07
Last Posted Date
2017-09-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
510
Registration Number
NCT02286362
Locations
๐Ÿ‡ซ๐Ÿ‡ท

CROM, Osny, France

๐Ÿ‡ซ๐Ÿ‡ท

C H Du Pays D'Aix En Provence; Hopital De Jour, Aix En Provence, France

๐Ÿ‡ซ๐Ÿ‡ท

Clinique Du Docteur Calabet; Cromg, Agen, France

and more 94 locations

Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration

Phase 1
Active, not recruiting
Conditions
Age-Related Macular Degeneration
Interventions
First Posted Date
2014-11-07
Last Posted Date
2025-04-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT02286089

A Study of RO6926496 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2014-11-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
48
Registration Number
NCT02281786
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