MedPath

Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Observational Study Examining the Use of Triple Combination Therapy With Boceprevir, Peginterferon Alfa-2a and Ribavirin in the Re-Treatment of Chronic Hepatitis C Patients

Terminated
Conditions
Hepatitis C, Chronic
Interventions
Drug: Pegylated Interferon (Peginterferon) Alfa-2a
First Posted Date
2014-04-21
Last Posted Date
2016-12-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT02118597

A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis

Phase 4
Completed
Conditions
Wegener's Granulomatosis or Microscopic Polyangiitis
Interventions
First Posted Date
2014-04-16
Last Posted Date
2022-07-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
30
Registration Number
NCT02115997
Locations
🇮🇳

Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute; Department of Rheumatologz, Mumbai, Maharashtra, India

🇮🇳

St. John's Medical College Hospital; Rheumatology, Bangalore, India

🇮🇳

Medanta-The Medicity, Gurgaon, Haryana, India

and more 7 locations

A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 2)

Phase 2
Completed
Conditions
Bladder Cancer
Interventions
First Posted Date
2014-04-09
Last Posted Date
2024-03-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
310
Registration Number
NCT02108652
Locations
🇺🇸

Mayo Clinic Cancer Center, Jacksonville, Florida, United States

🇺🇸

Stanford Cancer Center, Stanford, California, United States

🇺🇸

Willamette Valley Cancer Ctr - 520 Country Club, Eugene, Oregon, United States

and more 74 locations

European, Open-label, Prospective, Multinational, Multicenter Study in Adult Subjects With Type 1 or Type 2 Diabetes Previously on MDI or CSII Therapy. Subjects Home Setting is Considered Routine Practice.

Not Applicable
Completed
Conditions
Type 2 Diabetes, Type 1 Diabetes
Interventions
Device: Accu-Chek® Insight Insulin Pump
First Posted Date
2014-04-07
Last Posted Date
2016-09-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT02105103

A 2-Part Study to Evaluate the Safety of Supra-Therapeutic Doses of RO4602522 and to Investigate the Effect of RO4602522 on the QTc Interval

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Other: Placebo RO4602522
Other: moxifloxacin placebo
First Posted Date
2014-04-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
203
Registration Number
NCT02104648

A Study Evaluating the Perception of Insertion Pain With Accu-Chek FlexLink and FlexLink Plus Insulin Pump Devices Under Real Life Conditions in Diabetic Patients.

Not Applicable
Completed
Conditions
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
Interventions
Device: Accu-Chek FlexLink
Device: Accu-Chek FlexLink Plus
First Posted Date
2014-04-04
Last Posted Date
2017-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT02103595

A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate Asthma

Phase 3
Completed
Conditions
Asthma
Interventions
First Posted Date
2014-04-04
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
313
Registration Number
NCT02104674

Multicenter, Post-marketing, Non-interventional, Observational Study in RA Patients Treated With RoActemra/Actemra (Tocilizumab)

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2014-04-02
Last Posted Date
2017-12-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
400
Registration Number
NCT02101307
Locations
🇨🇳

Peking University Third Hospital, Beijing, China

🇨🇳

West China Hospital, Sichuan University, Chengdu, China

🇨🇳

Sichuan Provincial People's Hospital, Chengdu, China

and more 22 locations

A Study of the Efficacy and Safety of Etrolizumab in Participants With Ulcerative Colitis Who Have Been Previously Exposed to Tumor Necrosis Factor (TNF) Inhibitors

Phase 3
Completed
Conditions
Ulcerative Colitis
Interventions
Drug: Etrozulimab
Drug: Placebo
First Posted Date
2014-04-01
Last Posted Date
2021-08-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
609
Registration Number
NCT02100696
Locations
🇺🇸

Louisiana Research Center, LLC, Shreveport, Louisiana, United States

🇧🇪

CHU de Liège; Tour de Pathologie, Liège, Belgium

🇺🇸

Gastroenterology Center of the Midsouth, P.C., Memphis, Tennessee, United States

and more 181 locations
© Copyright 2025. All Rights Reserved by MedPath