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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)

Phase 2
Completed
Conditions
Down Syndrome
Interventions
Drug: Placebo
First Posted Date
2013-12-31
Last Posted Date
2017-10-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
173
Registration Number
NCT02024789
Locations
🇮🇹

Policlinico Universitario "Agostino Gemelli";Dip. Tutela Salute Donna Bambino Adolescente, Roma, Lazio, Italy

🇲🇽

Clínica Para la Atención del Neurodesarrollo, Aguascalientes, Mexico

🇲🇽

Hospital Universitario Dr. Jose Eleuterio Gonzalez; Pediatria, Monterrey, Mexico

and more 34 locations

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Other: High Fat and Calorie Meal
Other: Standard Meal
First Posted Date
2013-12-30
Last Posted Date
2016-10-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
42
Registration Number
NCT02023125

A Study of the Safety, Tolerability and Pharmacokientics of RO5545965 in Patients With Schizophrenia on Risperidone

Phase 1
Completed
Conditions
Schizophrenia
Interventions
First Posted Date
2013-12-24
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
32
Registration Number
NCT02019329

A Study Exmining the Effect of Multiple Doses of Bitopertin on the Single Dose Pharmacokinetics of Midazolam in Healthy Volunteers.

Phase 1
Withdrawn
Conditions
Healthy Volunteer
Interventions
First Posted Date
2013-12-24
Last Posted Date
2017-10-25
Lead Sponsor
Hoffmann-La Roche
Registration Number
NCT02019290

A Study of Pertuzumab and Trastuzumab Subcutaneous (SC) Treatment in Combination With a Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer

First Posted Date
2013-12-24
Last Posted Date
2018-09-13
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
50
Registration Number
NCT02019277
Locations
🇦🇺

Fiona Stanley Hospital, Murdoch, Western Australia, Australia

🇦🇺

St George Hospital; Cancer Care Centre, Kogarah, New South Wales, Australia

🇦🇺

Port Macquarie Base Hospital, Port Macquarie, New South Wales, Australia

and more 10 locations

A Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of RO6864018 in Male, Healthy, Asian Participants

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2013-12-19
Last Posted Date
2017-03-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
48
Registration Number
NCT02015715
Locations
🇸🇬

Changi General Hospital; Clinical Trial & Research unit, Singapore, Singapore

A Study of Herceptin (Trastuzumab) in Combination Chemotherapy in Patients With Metastatic or Locally Advanced Breast Cancer

Phase 1
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2013-12-19
Last Posted Date
2015-03-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
69
Registration Number
NCT02015676

A Study of Avastin (Bevacizumab) and Xeloda (Capecitabine) in Patients With Advanced or Metastatic Liver Cancer

Phase 2
Completed
Conditions
Liver Cancer
Interventions
First Posted Date
2013-12-17
Last Posted Date
2014-06-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT02013830

A Study of Tarceva (Erlotinib) in Patients With Advanced Non-Small Cell Lung Cancer Naive to Chemotherapy

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2013-12-17
Last Posted Date
2014-12-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT02013206

A Phase 1b Study of Atezolizumab in Combination With Erlotinib or Alectinib in Participants With Non-Small Cell Lung Cancer (NSCLC)

Phase 1
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2013-12-17
Last Posted Date
2020-04-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
52
Registration Number
NCT02013219
Locations
🇺🇸

Yale University School Of Medicine, New Haven, Connecticut, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇭🇰

The Chinese University of Hong Kong, Shatin, Hong Kong

and more 14 locations
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