University of Pennsylvania

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1740-11-14

Employees: 5K

Market Cap: -

Website: http://www.upenn.edu

Clinical Trials

Serial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung Cancer

Not Applicable

Terminated

Conditions: Non-small Cell Lung Cancer
Starting Pemetrexed Based Therapy
Unresectable Cancer

Interventions: Drug: Baseline 18F-thymidine (FLT) PET/CT
Drug: Post-therapy 18F-thymidine (FLT) PET/CT to assess for pemetrexed induced tumor FLT "flare"
Drug: Post-therapy 18F-thymidine (FLT) PET/CT to assess for pemetrexed induced changes in tumor proliferation

First Posted Date: 2014-10-24

Last Posted Date: 2021-05-12

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 3

Registration Number: NCT02274038

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Individualized Comparative Effectiveness of Models Optimizing Patient Safety and Resident Education.

Not Applicable

Completed

Conditions: Education, Medical
Safety
Sleep

Interventions: Behavioral: Flexible Duty Hour Schedule

First Posted Date: 2014-10-24

Last Posted Date: 2020-09-04

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 3500

Registration Number: NCT02274818

Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell Disease

Not Applicable

Completed

Conditions: Sickle Cell Disease

Interventions: Behavioral: Problem-Solving Skills Training for Disease Management

First Posted Date: 2014-10-23

Last Posted Date: 2016-01-07

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 83

Registration Number: NCT02273310

Handoffs and Transitions in Critical Care

Not Applicable

Completed

Conditions: Intensive Care Units
Patient Safety
Healthcare Team
Patient Handoff
Communication

Interventions: Behavioral: Standardized handoff

First Posted Date: 2014-10-17

Last Posted Date: 2020-06-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 1000

Registration Number: NCT02267174

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States

The Causal Impact of Online Social Media on Physical Activity: A Randomized Controlled Trial

Not Applicable

Completed

Conditions: Physical Activity

Interventions: Behavioral: Social network-assisted fitness program
Behavioral: Media-assisted fitness program
Behavioral: Basic fitness program

First Posted Date: 2014-10-17

Last Posted Date: 2014-10-17

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 217

Registration Number: NCT02267369

Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF

Phase 2

Completed

Conditions: Heart Failure
Diastolic Heart Failure

Interventions: Drug: KNO3
Drug: KCl

First Posted Date: 2014-10-03

Last Posted Date: 2017-10-03

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 12

Registration Number: NCT02256345

Locations: 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Exploratory Study of Circadian Relationships Between Social Behavior, Blood Pressure and Metabolomics

Completed

Conditions: Healthy

First Posted Date: 2014-09-26

Last Posted Date: 2020-01-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 6

Registration Number: NCT02249793

Locations: 🇺🇸
Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania, United States

Process Versus Outcomes Incentives for Lipid Management

Not Applicable

Completed

Conditions: Diabetes
Cardiovascular Disease

Interventions: Behavioral: Outcome Incentive
Behavioral: Process Incentive

First Posted Date: 2014-09-23

Last Posted Date: 2019-02-26

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 764

Registration Number: NCT02246959

Locations: 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

Phase 2

Completed

Conditions: Cognition Disorder
Traumatic Brain Injury
Attention Deficit Disorder

Interventions: Drug: Methylphenidate

First Posted Date: 2014-08-26

Last Posted Date: 2019-11-15

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 11

Registration Number: NCT02225106

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood

Completed

Conditions: Memory Disorders
Perceptual Disorders
Intellectual Disability

First Posted Date: 2014-08-25

Last Posted Date: 2019-06-18

Lead Sponsor: University of Pennsylvania

Target Recruit Count: 360

Registration Number: NCT02225041

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
Children's Memorial Hospital, Chicago, Chicago, Illinois, United States
🇺🇸
Johns Hopkins Children's Center, Baltimore, Maryland, United States

and more 28 locations

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