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NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

Phase 2
Completed
Conditions
Extensive Stage Small Cell Lung Cancer
Recurrent Small Cell Lung Cancer
Interventions
Other: pharmacological study
Other: laboratory biomarker analysis
First Posted Date
2008-10-16
Last Posted Date
2014-05-12
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
15
Registration Number
NCT00773955
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Paclitaxel and Trastuzumab With or Without Lapatinib in Treating Patients With Stage II or Stage III Breast Cancer That Can Be Removed by Surgery

Phase 3
Active, not recruiting
Conditions
Male Breast Carcinoma
Stage IIA Breast Cancer AJCC v6 and v7
Stage IIIC Breast Cancer AJCC v7
Stage IIB Breast Cancer AJCC v6 and v7
Stage IIIA Breast Cancer AJCC v7
Stage IIIB Breast Cancer AJCC v7
Interventions
First Posted Date
2008-10-10
Last Posted Date
2025-06-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
305
Registration Number
NCT00770809
Locations
🇺🇸

Dana-Farber Cancer Institute at Boston Medical Center - Brighton, Brighton, Massachusetts, United States

🇺🇸

Banner University Medical Center - Tucson, Tucson, Arizona, United States

🇺🇸

Sparks Regional Medical Center, Fort Smith, Arkansas, United States

and more 313 locations

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

Phase 3
Completed
Conditions
Breast Ductal Carcinoma In Situ
Interventions
Other: Laboratory Biomarker Analysis
Radiation: Whole Breast Irradiation
First Posted Date
2008-10-09
Last Posted Date
2025-06-12
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
2014
Registration Number
NCT00769379
Locations
🇺🇸

Northeast Alabama Regional Medical Center, Anniston, Alabama, United States

🇺🇸

Providence Hospital, Mobile, Alabama, United States

🇺🇸

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States

and more 1248 locations

FAU in Treating Patients With Advanced Solid Tumors or Lymphoma

Phase 1
Completed
Conditions
Adult Nasal Type Extranodal NK/T-cell Lymphoma
Angioimmunoblastic T-cell Lymphoma
Nodal Marginal Zone B-cell Lymphoma
Cutaneous B-cell Non-Hodgkin Lymphoma
Adult Grade III Lymphomatoid Granulomatosis
Anaplastic Large Cell Lymphoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Recurrent Adult Burkitt Lymphoma
Recurrent Adult Diffuse Large Cell Lymphoma
Recurrent Adult Diffuse Mixed Cell Lymphoma
Interventions
Other: positron emission tomography
Other: laboratory biomarker analysis
Other: pharmacological study
Other: pharmacogenomic studies
First Posted Date
2008-10-09
Last Posted Date
2014-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
12
Registration Number
NCT00769288
Locations
🇺🇸

Wayne State University, Detroit, Michigan, United States

Nortriptyline for Idiopathic Gastroparesis

Phase 3
Completed
Conditions
Idiopathic Gastroparesis
Interventions
Drug: Placebo (for nortriptyline)
First Posted Date
2008-10-03
Last Posted Date
2020-05-14
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
130
Registration Number
NCT00765895
Locations
🇺🇸

California Pacific Medical Center, San Francisco, California, United States

🇺🇸

Stanford University, Stanford, California, United States

🇺🇸

University of Michigan Medical Center, Ann Arbor, Michigan, United States

and more 4 locations

Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma

Phase 2
Completed
Conditions
Stage I Colon Cancer
Stage IIIC Rectal Cancer
Adenomatous Polyp
Stage I Rectal Cancer
Stage IIC Colon Cancer
Recurrent Colon Cancer
Stage IIA Rectal Cancer
Stage IIB Colon Cancer
Stage IIIA Colon Cancer
Stage IIB Rectal Cancer
Interventions
Other: placebo
Other: laboratory biomarker analysis
First Posted Date
2008-09-18
Last Posted Date
2015-01-06
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
45
Registration Number
NCT00754494
Locations
🇺🇸

VA Long Beach Healthcare System, Long Beach, California, United States

🇺🇸

Chao Family Comprehensive Cancer Center, Orange, California, United States

🇺🇸

University of Illinois at Chicago, Chicago, Illinois, United States

Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary

Phase 2
Completed
Conditions
Ovarian Steroid Cell Tumor
Malignant Ovarian Epithelial Tumor
Ovarian Sex Cord-Stromal Tumor
Ovarian Gynandroblastoma
Ovarian Granulosa Cell Tumor
Ovarian Sex Cord-Stromal Tumor of Mixed or Unclassified Cell Types
Ovarian Sertoli-Leydig Cell Tumor
Ovarian Sex Cord Tumor With Annular Tubules
Interventions
Biological: Bevacizumab
Other: Laboratory Biomarker Analysis
First Posted Date
2008-09-08
Last Posted Date
2019-07-23
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
36
Registration Number
NCT00748657
Locations
🇺🇸

Los Angeles County-USC Medical Center, Los Angeles, California, United States

🇺🇸

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

University of Colorado Hospital, Aurora, Colorado, United States

and more 33 locations

Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Phase 1
Completed
Conditions
Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)
Adult Erythroleukemia (M6a)
Adult Pure Erythroid Leukemia (M6b)
Acute Myeloid Leukemia
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Interventions
First Posted Date
2008-08-28
Last Posted Date
2014-09-12
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
95
Registration Number
NCT00742625
Locations
🇺🇸

Washington Hospital Center, Washington, District of Columbia, United States

🇺🇸

Lombardi Comprehensive Cancer Center at Georgetown University, Washington, District of Columbia, United States

🇺🇸

Florida Hospital, Orlando, Florida, United States

and more 19 locations

Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin Lymphoma

Phase 1
Active, not recruiting
Conditions
Solid Neoplasm
Ann Arbor Stage III Non-Hodgkin Lymphoma
Ann Arbor Stage IV Non-Hodgkin Lymphoma
Interventions
Other: Laboratory Biomarker Analysis
Other: Pharmacological Study
First Posted Date
2008-08-25
Last Posted Date
2025-02-20
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
81
Registration Number
NCT00740805
Locations
🇺🇸

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment

Phase 2
Recruiting
Conditions
Weight Loss
Eating
Obesity
Electric Stimulation Therapy
Interventions
Other: Sham/no-stimulation
Device: Transcranial Direct Current Stimulation (TDCS)
First Posted Date
2008-08-21
Last Posted Date
2025-06-17
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
148
Registration Number
NCT00739362
Locations
🇺🇸

NIDDK, Phoenix, Phoenix, Arizona, United States

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