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NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Phase 1
Completed
Conditions
Adult Grade III Lymphomatoid Granulomatosis
Anaplastic Large Cell Lymphoma
Angioimmunoblastic T-cell Lymphoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Intraocular Lymphoma
Nodal Marginal Zone B-cell Lymphoma
Recurrent Adult Burkitt Lymphoma
Recurrent Adult Immunoblastic Large Cell Lymphoma
Recurrent Adult Lymphoblastic Lymphoma
Recurrent Adult T-cell Leukemia/Lymphoma
Interventions
First Posted Date
2004-12-09
Last Posted Date
2013-01-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
24
Registration Number
NCT00098891
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes

Phase 1
Completed
Conditions
Acute Undifferentiated Leukemia
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia With Maturation (M2)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)
Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
Interventions
Other: laboratory biomarker analysis
Other: pharmacological study
First Posted Date
2004-12-09
Last Posted Date
2013-01-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00098826
Locations
🇺🇸

Case Western Reserve University, Cleveland, Ohio, United States

UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants

Phase 1
Completed
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
First Posted Date
2004-12-09
Last Posted Date
2012-12-17
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00098969
Locations
🇺🇸

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

🇬🇧

Leicester Royal Infirmary, Leicester, England, United Kingdom

Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma

Phase 2
Completed
Conditions
Smoldering Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance
Multiple Myeloma
Interventions
Drug: placebo
Other: laboratory biomarker analysis
First Posted Date
2004-12-09
Last Posted Date
2016-12-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
23
Registration Number
NCT00099047
Locations
🇺🇸

Cleveland Clinic Foundation, Cleveland, Ohio, United States

7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer

Phase 2
Completed
Conditions
Recurrent Small Cell Lung Cancer
Extensive Stage Small Cell Lung Cancer
Interventions
First Posted Date
2004-12-09
Last Posted Date
2018-07-23
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
19
Registration Number
NCT00098956
Locations
🇨🇦

Princess Margaret Hospital Phase 2 Consortium, Toronto, Ontario, Canada

Flavopiridol in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia

Phase 2
Terminated
Conditions
B-cell Chronic Lymphocytic Leukemia
Refractory Chronic Lymphocytic Leukemia
Prolymphocytic Leukemia
Interventions
First Posted Date
2004-12-08
Last Posted Date
2016-10-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
64
Registration Number
NCT00098371
Locations
🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma

Phase 3
Active, not recruiting
Conditions
DS Stage I Multiple Myeloma
DS Stage II Multiple Myeloma
DS Stage III Multiple Myeloma
Interventions
Other: Laboratory Biomarker Analysis
First Posted Date
2004-12-08
Last Posted Date
2025-05-18
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
452
Registration Number
NCT00098475
Locations
🇺🇸

Saint Luke's Cancer Institute - Boise, Boise, Idaho, United States

🇺🇸

The Medical Center of Aurora, Aurora, Colorado, United States

🇺🇸

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

and more 135 locations

Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Phase 2
Completed
Conditions
Recurrent Metastatic Squamous Neck Cancer With Occult Primary
Recurrent Squamous Cell Carcinoma of the Hypopharynx
Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
Metastatic Squamous Neck Cancer With Occult Primary
Recurrent Squamous Cell Carcinoma of the Larynx
Recurrent Squamous Cell Carcinoma of the Nasopharynx
Recurrent Squamous Cell Carcinoma of the Oropharynx
Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Salivary Gland Squamous Cell Carcinoma
Stage IV Squamous Cell Carcinoma of the Hypopharynx
Interventions
Other: laboratory biomarker analysis
First Posted Date
2004-12-08
Last Posted Date
2014-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
88
Registration Number
NCT00098631
Locations
🇺🇸

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes

Phase 1
Completed
Conditions
Accelerated Phase Chronic Myelogenous Leukemia
Adult Acute Basophilic Leukemia
Adult Acute Eosinophilic Leukemia
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia With Maturation (M2)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Interventions
First Posted Date
2004-12-08
Last Posted Date
2013-09-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT00098423
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

FR901228 in Treating Patients With Refractory Stomach Cancer or Gastroesophageal Junction Cancer

Phase 2
Terminated
Conditions
Adenocarcinoma of the Esophagus
Adenocarcinoma of the Stomach
Recurrent Esophageal Cancer
Recurrent Gastric Cancer
Interventions
Other: laboratory biomarker analysis
First Posted Date
2004-12-08
Last Posted Date
2013-07-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
20
Registration Number
NCT00098527
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

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