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NATIONAL INSTITUTES OF HEALTH

NATIONAL INSTITUTES OF HEALTH logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1948-01-01
Employees
1K
Market Cap
-
Website
http://www.nidcr.nih.gov

Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma

Phase 3
Active, not recruiting
Conditions
DS Stage I Multiple Myeloma
DS Stage II Multiple Myeloma
DS Stage III Multiple Myeloma
Interventions
Other: Laboratory Biomarker Analysis
First Posted Date
2004-12-08
Last Posted Date
2025-05-18
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
452
Registration Number
NCT00098475
Locations
🇺🇸

Saint Luke's Cancer Institute - Boise, Boise, Idaho, United States

🇺🇸

The Medical Center of Aurora, Aurora, Colorado, United States

🇺🇸

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

and more 135 locations

Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Phase 2
Completed
Conditions
Recurrent Metastatic Squamous Neck Cancer With Occult Primary
Recurrent Squamous Cell Carcinoma of the Hypopharynx
Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
Metastatic Squamous Neck Cancer With Occult Primary
Recurrent Squamous Cell Carcinoma of the Larynx
Recurrent Squamous Cell Carcinoma of the Nasopharynx
Recurrent Squamous Cell Carcinoma of the Oropharynx
Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Salivary Gland Squamous Cell Carcinoma
Stage IV Squamous Cell Carcinoma of the Hypopharynx
Interventions
Other: laboratory biomarker analysis
First Posted Date
2004-12-08
Last Posted Date
2014-01-07
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
88
Registration Number
NCT00098631
Locations
🇺🇸

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes

Phase 1
Completed
Conditions
Accelerated Phase Chronic Myelogenous Leukemia
Adult Acute Basophilic Leukemia
Adult Acute Eosinophilic Leukemia
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia With Maturation (M2)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Interventions
First Posted Date
2004-12-08
Last Posted Date
2013-09-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT00098423
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

FR901228 in Treating Patients With Refractory Stomach Cancer or Gastroesophageal Junction Cancer

Phase 2
Terminated
Conditions
Adenocarcinoma of the Esophagus
Adenocarcinoma of the Stomach
Recurrent Esophageal Cancer
Recurrent Gastric Cancer
Interventions
Other: laboratory biomarker analysis
First Posted Date
2004-12-08
Last Posted Date
2013-07-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
20
Registration Number
NCT00098527
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

Phase 2
Terminated
Conditions
Clear Cell Renal Cell Carcinoma
Papillary Renal Cell Carcinoma
Recurrent Renal Cell Cancer
Stage III Renal Cell Cancer
Stage IV Renal Cell Cancer
Interventions
Biological: recombinant interferon alfa
Other: laboratory biomarker analysis
First Posted Date
2004-12-08
Last Posted Date
2013-07-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
40
Registration Number
NCT00098618
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

Phase 2
Completed
Conditions
Central Nervous System Metastases
HER2-positive Breast Cancer
Male Breast Cancer
Recurrent Breast Cancer
Stage IV Breast Cancer
Tumors Metastatic to Brain
Interventions
Other: laboratory biomarker analysis
Procedure: quality-of-life assessment
Other: questionnaire administration
First Posted Date
2004-12-08
Last Posted Date
2013-06-06
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
37
Registration Number
NCT00098605
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

CCI-779 and EKB-569 in Treating Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
First Posted Date
2004-12-08
Last Posted Date
2013-06-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT00098501
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia

Phase 1
Terminated
Conditions
B-cell Chronic Lymphocytic Leukemia
Prolymphocytic Leukemia
Refractory Chronic Lymphocytic Leukemia
Interventions
Biological: rituximab
First Posted Date
2004-12-08
Last Posted Date
2013-06-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
30
Registration Number
NCT00098488
Locations
🇺🇸

Ohio State University Medical Center, Columbus, Ohio, United States

BAY 43-9006 (Sorafenib) to Treat Relapsed Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-Small-Cell Lung Carcinoma
Interventions
Drug: BAY 43-9006 (Sorafenib)
First Posted Date
2004-12-06
Last Posted Date
2012-05-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
37
Registration Number
NCT00098254
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Podocyte Retinoids

Phase 2
Completed
Conditions
Glomerulosclerosis, Focal Segmental
Collapsing Glomerulopathy
Interventions
First Posted Date
2004-12-02
Last Posted Date
2017-12-13
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
12
Registration Number
NCT00098020
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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