NATIONAL INSTITUTES OF HEALTH

🇺🇸United States

Country: 🇺🇸United States

Ownership: Subsidiary, Private

Established: 1948-01-01

Employees: 1K

Market Cap: -

Website: http://www.nidcr.nih.gov

Clinical Trials

Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery

Phase 1

Completed

Conditions: Unspecified Adult Solid Tumor, Protocol Specific

Interventions: Drug: oxaliplatin
Drug: leucovorin calcium
Drug: fluorouracil
Drug: capecitabine
Other: pharmacological study

First Posted Date: 2003-01-27

Last Posted Date: 2013-12-11

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 50

Registration Number: NCT00043121

Locations: 🇺🇸
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma

Phase 1

Completed

Conditions: AIDS-related Peripheral/Systemic Lymphoma
AIDS-related Primary CNS Lymphoma
Anaplastic Large Cell Lymphoma
Angioimmunoblastic T-cell Lymphoma
Chondrosarcoma
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Intraocular Lymphoma
Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Metastatic Osteosarcoma
Nodal Marginal Zone B-cell Lymphoma

Interventions: Drug: tanespimycin
Other: pharmacological study

First Posted Date: 2003-01-27

Last Posted Date: 2013-02-07

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 60

Registration Number: NCT00004241

Locations: 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Bortezomib in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 2

Terminated

Conditions: Recurrent Non-small Cell Lung Cancer
Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer

Interventions: Drug: bortezomib

First Posted Date: 2003-01-27

Last Posted Date: 2013-01-16

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 35

Registration Number: NCT00040768

Locations: 🇺🇸
Abramson Cancer Center of The University of Pennsylvania, Philadelphia, Pennsylvania, United States

Carboxyamidotriazole in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer

Phase 3

Completed

Conditions: Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer
Stage IIIA Non-small Cell Lung Cancer

Interventions: Drug: carboxyamidotriazole
Other: placebo
Procedure: quality-of-life assessment
Other: laboratory biomarker analysis

First Posted Date: 2003-01-27

Last Posted Date: 2014-05-20

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 186

Registration Number: NCT00003869

Locations: 🇺🇸
North Central Cancer Treatment Group, Rochester, Minnesota, United States

National Lung Screening Trial (NLST) Screening

Phase 3

Completed

Conditions: Lung Cancer

Interventions: Device: low-dose helical computed tomography
Device: chest radiography

First Posted Date: 2003-01-27

Last Posted Date: 2014-05-20

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 53454

Registration Number: NCT00047385

Locations: 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸
St Elizabeth Health Center, Youngstown, Ohio, United States
🇺🇸
Marshfield Clinic Research Foundation, Marshfield, Wisconsin, United States

and more 30 locations

Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer

Phase 2

Completed

Conditions: Duct Cell Adenocarcinoma of the Pancreas
Stage IV Pancreatic Cancer
Acinar Cell Adenocarcinoma of the Pancreas
Recurrent Pancreatic Cancer
Stage III Pancreatic Cancer

Interventions: Drug: paclitaxel
Drug: bryostatin 1

First Posted Date: 2003-01-27

Last Posted Date: 2021-06-11

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 19

Registration Number: NCT00031694

Locations: 🇺🇸
Montefiore Medical Center, Bronx, New York, United States

Oblimersen and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia

Phase 2

Completed

Conditions: Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Relapsing Chronic Myelogenous Leukemia
Chronic Phase Chronic Myelogenous Leukemia

Interventions: Biological: oblimersen sodium
Drug: imatinib mesylate
Other: laboratory biomarker analysis

First Posted Date: 2003-01-27

Last Posted Date: 2013-06-04

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 43

Registration Number: NCT00049192

Locations: 🇺🇸
Cancer and Leukemia Group B, Chicago, Illinois, United States

Oxaliplatin in Treating Patients With Liver Cancer

Phase 2

Completed

Conditions: Localized Unresectable Adult Primary Liver Cancer
Adult Primary Hepatocellular Carcinoma
Advanced Adult Primary Liver Cancer
Recurrent Adult Primary Liver Cancer

Interventions: Drug: oxaliplatin
Other: laboratory biomarker analysis

First Posted Date: 2003-01-27

Last Posted Date: 2013-06-18

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 32

Registration Number: NCT00052364

Locations: 🇺🇸
City of Hope, Duarte, California, United States

Imatinib Mesylate in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

Phase 2

Completed

Conditions: Primary Peritoneal Cavity Cancer
Recurrent Ovarian Epithelial Cancer

Interventions: Drug: imatinib mesylate
Other: laboratory biomarker analysis

First Posted Date: 2003-01-27

Last Posted Date: 2013-02-20

Lead Sponsor: National Cancer Institute (NCI)

Target Recruit Count: 60

Registration Number: NCT00041041

Locations: 🇺🇸
Gynecologic Oncology Group, Philadelphia, Pennsylvania, United States

Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Phase 3

Completed

Conditions: Multiple Myeloma and Plasma Cell Neoplasm

First Posted Date: 2003-01-27

Last Posted Date: 2014-04-04

Lead Sponsor: National Cancer Institute (NCI)

Registration Number: NCT00033332

Locations: 🇺🇸
Veterans Affairs Medical Center - Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸
CCOP - Scott and White Hospital, Temple, Texas, United States
🇺🇸
Veterans Affairs Medical Center - Madison, Madison, Wisconsin, United States

and more 75 locations

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