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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Safety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host Disease

Phase 1
Terminated
Conditions
Chronic Graft Versus Host Disease cGVHD
Interventions
First Posted Date
2018-02-06
Last Posted Date
2023-11-22
Lead Sponsor
Amgen
Target Recruit Count
32
Registration Number
NCT03422627
Locations
🇺🇸

Texas Oncology Baylor, Dallas, Texas, United States

🇺🇸

Emory University, Atlanta, Georgia, United States

🇫🇷

Hôpital Saint Louis, Paris Cedex 10, France

and more 11 locations

Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis

Phase 1
Terminated
Conditions
Rheumatoid Arthritis RA
Interventions
First Posted Date
2018-01-25
Last Posted Date
2021-06-22
Lead Sponsor
Amgen
Target Recruit Count
36
Registration Number
NCT03410056
Locations
🇪🇸

Research Site, A Coruña, Galicia, Spain

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia

Phase 4
Completed
Conditions
Homozygous Familial Hypercholesterolemia HoFH
Interventions
First Posted Date
2018-01-18
Last Posted Date
2024-05-29
Lead Sponsor
Amgen
Target Recruit Count
30
Registration Number
NCT03403374
Locations
🇮🇳

Research Site, Lucknow, Uttar Pradesh, India

A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC

Phase 1
Suspended
Conditions
Small Cell Lung Cancer
Interventions
First Posted Date
2018-01-05
Last Posted Date
2023-09-15
Lead Sponsor
Amgen
Target Recruit Count
6
Registration Number
NCT03392064
Locations
🇺🇸

Research Site, Houston, Texas, United States

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer

Phase 3
Completed
Conditions
Chemotherapy-induced Thrombocytopenia
Interventions
First Posted Date
2017-12-05
Last Posted Date
2025-01-20
Lead Sponsor
Amgen
Target Recruit Count
165
Registration Number
NCT03362177
Locations
🇵🇹

Centro Hospitalar Universitario de Sao Joao, EPE - Hospital Sao Joao, Porto, Portugal

🇷🇺

Autonomic SHI Republican clinical oncology dispensary of MoH of the Republic of Tatarstan, Kazan, Russian Federation

🇷🇺

Clinical hospital 2, Group of companies medsi, Moscow, Russian Federation

and more 113 locations

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Lymphoma.

Phase 3
Withdrawn
Conditions
Chemotherapy-induced Thrombocytopenia
Interventions
Other: Placebo
Biological: Romiplostim
First Posted Date
2017-11-17
Last Posted Date
2018-01-19
Lead Sponsor
Amgen
Registration Number
NCT03343847

Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Phase 1
Completed
Conditions
Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Interventions
First Posted Date
2017-11-14
Last Posted Date
2024-10-17
Lead Sponsor
Amgen
Target Recruit Count
31
Registration Number
NCT03340766
Locations
🇪🇸

Research Site, Madrid, Spain

Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs)

Phase 4
Completed
Conditions
Urea Cycle Disorder
Interventions
Drug: NaPBA
First Posted Date
2017-11-07
Last Posted Date
2024-07-01
Lead Sponsor
Amgen
Target Recruit Count
16
Registration Number
NCT03335488
Locations
🇺🇸

Mount Sinai School of Medicine, New York, New York, United States

🇪🇸

Hospital Materno-Infantil (HRU Carlos Haya), Málaga, Andalucia, Spain

🇮🇹

Bambino Gesù Children's Research Hospital, Rome, Italy

and more 8 locations

Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)

Phase 1
Active, not recruiting
Conditions
Small Cell Lung Carcinoma
Interventions
Drug: CRS Mitigation Strategies
First Posted Date
2017-10-24
Last Posted Date
2025-02-14
Lead Sponsor
Amgen
Target Recruit Count
269
Registration Number
NCT03319940
Locations
🇺🇸

The Ohio State University Wexner Medical Center - Thoracic Oncology Clinic, Columbus, Ohio, United States

🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

🇦🇹

Landeskrankenhaus Salzburg, Salzburg, Austria

and more 36 locations

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Phase 1
Completed
Conditions
Heart Failure
Interventions
First Posted Date
2017-10-24
Last Posted Date
2022-06-23
Lead Sponsor
Amgen
Target Recruit Count
12
Registration Number
NCT03318809
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

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