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Amgen, Inc.

Amgen, Inc. logo
🇺🇸United States
Ownership
Public
Established
1980-01-01
Employees
26.7K
Market Cap
$175.6B
Website
http://www.amgen.com

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy

Phase 2
Completed
Conditions
C3 Glomerulopathy (C3G)
Interventions
First Posted Date
2017-10-04
Last Posted Date
2025-03-13
Lead Sponsor
Amgen
Target Recruit Count
57
Registration Number
NCT03301467
Locations
🇬🇧

Clinical Site, Newcastle Upon Tyne, United Kingdom

🇺🇸

University of Utah, Salt Lake City, Utah, United States

🇺🇸

Clinical Trial Site, East Providence, Rhode Island, United States

and more 1 locations

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Phase 4
Completed
Conditions
Giant Cell Tumor of Bone
Interventions
First Posted Date
2017-10-04
Last Posted Date
2024-05-20
Lead Sponsor
Amgen
Target Recruit Count
85
Registration Number
NCT03301857
Locations
🇺🇸

Sarcoma Oncology Research Center LLC, Santa Monica, California, United States

🇺🇸

Mount Sinai Beth Israel Downtown, New York, New York, United States

🇺🇸

University of Minnesota Medical Center Fairview, Minneapolis, Minnesota, United States

and more 11 locations

Head-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT)

Phase 3
Completed
Conditions
Secondary Hyperparathyroidism
Chronic Kidney Disease
Interventions
First Posted Date
2017-10-03
Last Posted Date
2021-04-30
Lead Sponsor
Amgen
Target Recruit Count
637
Registration Number
NCT03299244
Locations
🇨🇳

Research Site, Taoyuan, Taiwan

Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study

Phase 3
Completed
Conditions
Thyroid Eye Disease
Graves' Orbitopathy
Interventions
Biological: Teprotumumab
Other: Placebo
First Posted Date
2017-10-02
Last Posted Date
2024-07-11
Lead Sponsor
Amgen
Target Recruit Count
83
Registration Number
NCT03298867
Locations
🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Bascom Palmer Eye Institute, Miami, Florida, United States

🇺🇸

Casey Eye Institute at Oregon Health and Science University, Portland, Oregon, United States

and more 11 locations

Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT)

Phase 2
Terminated
Conditions
High-risk Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2017-10-02
Last Posted Date
2020-09-11
Lead Sponsor
Amgen
Target Recruit Count
10
Registration Number
NCT03298412
Locations
🇨🇭

Research Site, Zurich, Switzerland

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Phase 1
Terminated
Conditions
Glioblastoma or Malignant Glioma
Interventions
First Posted Date
2017-09-28
Last Posted Date
2024-10-29
Lead Sponsor
Amgen
Target Recruit Count
30
Registration Number
NCT03296696
Locations
🇺🇸

University of California Los Angeles, Los Angeles, California, United States

🇳🇱

Vrije Universiteit Medisch Centrum, Amsterdam, Netherlands

🇩🇪

Universitaetsklinikum Wuerzburg, Würzburg, Germany

and more 7 locations

A Study to Assess AMG 701 Montherapy, or in Combination With Pomalidomide, With or Without, Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Phase 1
Terminated
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
First Posted Date
2017-09-19
Last Posted Date
2024-10-21
Lead Sponsor
Amgen
Target Recruit Count
174
Registration Number
NCT03287908
Locations
🇨🇦

University Health Network-Princess Margaret Cancer Centre, Toronto, Ontario, Canada

🇺🇸

Winship Cancer Institute Emory U, Atlanta, Georgia, United States

🇺🇸

University of Chicago Medical Center - Multiple Myeloma Research Consortium, Chicago, Illinois, United States

and more 31 locations

Post-Marketing Surveillance Study of OTEZLA

Completed
Conditions
Psoriasis
First Posted Date
2017-09-15
Last Posted Date
2022-04-29
Lead Sponsor
Amgen
Target Recruit Count
1086
Registration Number
NCT03284879
Locations
🇯🇵

Tugi dermatology clinic, Kitakyushu, Fukuoka, Japan

A Phase 1 Study to Evaluate PK, Safety and Tolerability of AMG 416

Phase 1
Completed
Conditions
Secondary Hyperparathyroidism
Interventions
Drug: Placebo
First Posted Date
2017-09-14
Last Posted Date
2020-02-10
Lead Sponsor
Amgen
Target Recruit Count
33
Registration Number
NCT03283098
Locations
🇨🇳

Research Site, Shanghai, Shanghai, China

Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients

Phase 1
Terminated
Conditions
Heart Failure
Healthy Volunteer
Interventions
Drug: Placebo PO
Drug: AMG 986 IV
Drug: Placebo IV
Drug: AMG 986 PO
First Posted Date
2017-09-08
Last Posted Date
2022-08-08
Lead Sponsor
Amgen
Target Recruit Count
182
Registration Number
NCT03276728
Locations
🇸🇬

Research Site, Singapore, Singapore

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