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JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial

Not Applicable

Completed

Conditions: Antibiotic Stewardship

Interventions: Other: Opt-Out Protocol

First Posted Date: 2018-05-07

Last Posted Date: 2025-02-06

Lead Sponsor: Duke University

Target Recruit Count: 762

Registration Number: NCT03517007

Locations: 🇺🇸
Iredell Health System, Statesville, North Carolina, United States
🇺🇸
Pennsylvania Presbyterian Hospital, Philadelphia, Pennsylvania, United States
🇺🇸
Southeastern Regional Medical Center, Lumberton, North Carolina, United States

and more 7 locations

Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting

Conditions: Breastfed Infants of Mothers on Select DOI
Lactating Women on Select DOI

First Posted Date: 2018-04-27

Last Posted Date: 2024-12-17

Lead Sponsor: Duke University

Target Recruit Count: 1600

Registration Number: NCT03511118

Locations: 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸
Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸
Loma Linda University Health, Loma Linda, California, United States

and more 19 locations

PaRTNer: Patient Reported Outcomes and Financial Toxicity in Head and Neck Cancer A Pilot, Survey Based Study

Not Applicable

Active, not recruiting

Conditions: Head and Neck Cancer

Interventions: Other: Demographics questionnaires and the FACT HN questionnaire

First Posted Date: 2018-04-24

Last Posted Date: 2025-05-25

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT03506451

Locations: 🇺🇸
Duke Cancer Center, Durham, North Carolina, United States

Addressing Palliative Care Needs Among Intensive Care Unit Family Members

Not Applicable

Completed

Conditions: Critical Illness
Family Members
Palliative Care
Psychological Distress
Informal Caregivers

Interventions: Other: Usual care
Behavioral: Needs-focused mobile app

First Posted Date: 2018-04-24

Last Posted Date: 2023-11-13

Lead Sponsor: Duke University

Target Recruit Count: 111

Registration Number: NCT03506438

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Coherence Imaging of the Cervical Epithelium With Scanning a/LCI

Not Applicable

Completed

Conditions: Cervical Dysplasia

Interventions: Device: scanning a/LCI

First Posted Date: 2018-04-19

Last Posted Date: 2021-02-18

Lead Sponsor: Duke University

Target Recruit Count: 45

Registration Number: NCT03502798

Locations: 🇺🇸
Jacobi Medical Center, Bronx, New York, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Quality of Life of Patients With Glioblastoma (GBM) Treated With Tumor-Treating Fields

Completed

Conditions: Malignant Glioma

Interventions: Device: NovoTTF

First Posted Date: 2018-04-18

Last Posted Date: 2021-06-09

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT03501134

Locations: 🇺🇸
The Preston Robert Tisch Brain Tumor Center at Duke, Durham, North Carolina, United States

Surgeon Infiltration QL Block Comparison

Phase 4

Completed

Conditions: Quadratus Lumborum Block
Surgical Wound Infiltration

Interventions: Procedure: QL Block
Drug: Liposomal Bupivicaine

First Posted Date: 2018-04-12

Last Posted Date: 2024-03-05

Lead Sponsor: Duke University

Target Recruit Count: 44

Registration Number: NCT03496610

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products

Phase 2

Completed

Conditions: Nicotine Dependence, Cigarettes

Interventions: Drug: Nicotine patch
Other: Placebo patch
Other: E-cigarettes
Other: Non-nicotine e-cigarettes

First Posted Date: 2018-04-10

Last Posted Date: 2023-02-08

Lead Sponsor: Duke University

Target Recruit Count: 94

Registration Number: NCT03492463

Locations: 🇺🇸
Duke Center for Smoking Cessation, Durham, North Carolina, United States

Disease-Modifying Treatments for Myasthenia Gravis

Completed

Conditions: Neurological Disorder
Autoimmune Diseases

Interventions: Drug: Azathioprine
Drug: Mycophenolate Mofetil

First Posted Date: 2018-04-06

Last Posted Date: 2021-02-03

Lead Sponsor: Duke University

Target Recruit Count: 167

Registration Number: NCT03490539

Locations: 🇨🇦
University of Alberta Hospital, Faculty of Medicine, Edmonton, Alberta, Canada
🇺🇸
University at Buffalo, SUNY, Buffalo, New York, United States
🇺🇸
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

and more 16 locations

Stigma, Self-management, & Quality of Life in SCD

Completed

Conditions: Quality of Life
Disease Self-Management
Sickle Cell Disease
Stigma, Social

First Posted Date: 2018-04-04

Last Posted Date: 2019-04-11

Lead Sponsor: Duke University

Target Recruit Count: 102

Registration Number: NCT03488264

Locations: 🇯🇲
Sickle Cell Unit, The University of the West Indies, Mona, Kingston 7, Jamaica
🇺🇸
Dominique Bulgin, Durham, North Carolina, United States

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