JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Dendreon Lymph Node Biopsy in Metastatic Castrate-Resistant Prostate Cancer

Phase 1

Completed

Conditions: Prostate Cancer

Interventions: Drug: Sipuleucel-T
Procedure: Lymph Node Biopsy

First Posted Date: 2014-01-15

Last Posted Date: 2020-03-31

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT02036918

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women

Not Applicable

Completed

Conditions: Weight Loss
Obesity

Interventions: Dietary Supplement: Protein supplementation
Behavioral: Diet counseling and group education lessons

First Posted Date: 2014-01-13

Last Posted Date: 2019-01-08

Lead Sponsor: Duke University

Target Recruit Count: 105

Registration Number: NCT02033655

Locations: 🇺🇸
Duke Universtiy Medical Center, Durham, North Carolina, United States

Let's be Well Red: Efficacy of Gudness Bars in Improving the Hemoglobin and Hematocrit Levels of Anemic Subjects

Not Applicable

Completed

Conditions: Treatment and Prevention of Anemia After Administration of Gudness Nutrition Bar

Interventions: Dietary Supplement: Education plus Gudness Nutritional Bar
Other: Education

First Posted Date: 2014-01-10

Last Posted Date: 2016-11-25

Lead Sponsor: Duke University

Target Recruit Count: 358

Registration Number: NCT02032615

Locations: 🇮🇳
Lets Be Well Red, Mumbai, Maharashtra, India

TXA vs. Amicar in Total Knee and Hip Arthroplasty

Phase 4

Completed

Conditions: Knee Arthritis
Blood Loss
Hip Arthritis

Interventions: Drug: TXA
Drug: Amicar

First Posted Date: 2014-01-09

Last Posted Date: 2018-12-05

Lead Sponsor: Duke University

Target Recruit Count: 246

Registration Number: NCT02030821

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE)

Not Applicable

Terminated

Conditions: ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy

Interventions: Procedure: ROSE
Device: 22 gauge Vizishot needles

First Posted Date: 2014-01-06

Last Posted Date: 2017-02-15

Lead Sponsor: Duke University

Target Recruit Count: 37

Registration Number: NCT02028052

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

RNA Extraction and Amplification From Biopsy Specimens in Subjects With Metastatic Renal Cell Carcinoma (AGS-NTS-017)

Not Applicable

Terminated

Conditions: Metastatic Renal Cell Carcinoma
Genitourinary Cancer (Bladder, Prostate or Testicular)

Interventions: Device: RNA extraction and amplification from biopsy specimens

First Posted Date: 2014-01-03

Last Posted Date: 2018-12-20

Lead Sponsor: Duke University

Target Recruit Count: 14

Registration Number: NCT02026960

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Isolation of Circulating Tumor Cells Using a Novel EMT-Based Capture Method

Not Applicable

Completed

Conditions: Metastatic Progressive Castration-resistant Prostate Cancer
Metastatic Progressive Breast Cancer

Interventions: Device: Mesenchymal-marker based ferrofluid (N-cadherin or O-cadherin based)

First Posted Date: 2014-01-01

Last Posted Date: 2018-12-20

Lead Sponsor: Duke University

Target Recruit Count: 46

Registration Number: NCT02025413

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Phenylephrine Versus Ephedrine in Pre-eclampsia

Phase 4

Terminated

Conditions: Pre-eclampsia

Interventions: Drug: Ephedrine
Drug: Phenylephrine

First Posted Date: 2014-01-01

Last Posted Date: 2020-10-14

Lead Sponsor: Duke University

Target Recruit Count: 13

Registration Number: NCT02025426

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Prostate Cancer Circulating Tumor Cells Based on Epithelial-Mesenchymal Transition Biology

Not Applicable

Withdrawn

Conditions: Prostate Cancer

Interventions: Device: Near infrared (NIR) emissive nanotechnology

First Posted Date: 2013-12-30

Last Posted Date: 2015-07-30

Lead Sponsor: Duke University

Registration Number: NCT02022904

Clinical Evaluation of Direct Dorsal Column Stimulation

Not Applicable

Terminated

Conditions: Failed Back Surgery Syndrome

Interventions: Device: Epidural trial lead
Device: Subdural trial lead

First Posted Date: 2013-12-25

Last Posted Date: 2017-02-08

Lead Sponsor: Duke University

Target Recruit Count: 6

Registration Number: NCT02020460

Locations: 🇺🇸
Duke University Health Systems, Durham, North Carolina, United States

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