JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Symptom Clusters in Children With Leukemia

Completed

Conditions: Childhood Leukemia

First Posted Date: 2012-10-17

Last Posted Date: 2018-11-06

Lead Sponsor: Duke University

Target Recruit Count: 338

Registration Number: NCT01708421

Locations: 🇺🇸
Children's Hospitals & Clinics of Minnesota, Minneapolis, Minnesota, United States
🇺🇸
Baylor College of Medicine/ Texas Children's Cancer Center, Houston, Texas, United States
🇺🇸
University of Arizona, Tucson, Arizona, United States

and more 1 locations

The MURDOCK Study Registry and Biorepository Horizon 1.5

Active, not recruiting

Conditions: Chronic Disease
Healthy Volunteers

Interventions: Genetic: Biomarker studies

First Posted Date: 2012-10-17

Last Posted Date: 2023-05-24

Lead Sponsor: Duke University

Target Recruit Count: 50000

Registration Number: NCT01708408

Locations: 🇺🇸
Duke Clinical Translational Science Institute-MURDOCK Study, Kannapolis, North Carolina, United States

The Effects of Respiratory Muscle Strength Training (RMST) on Inspiratory and Expiratory Muscle Strength in Adults and Children With Pompe Disease

Completed

Conditions: Pompe Disease

Interventions: Other: respiratory muscle strength training

First Posted Date: 2012-10-04

Last Posted Date: 2023-05-30

Lead Sponsor: Duke University

Target Recruit Count: 11

Registration Number: NCT01701154

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Time of Intravenous Acetaminophen Administration

Phase 4

Completed

Conditions: Osteoarthritis

Interventions: Drug: Acetaminophen

First Posted Date: 2012-10-04

Last Posted Date: 2014-09-05

Lead Sponsor: Duke University

Target Recruit Count: 126

Registration Number: NCT01699815

Locations: 🇺🇸
Durham Regional Hospital, Durham, North Carolina, United States

The CARRA Registry

Completed

Conditions: Mixed Connective Tissue Disease
Systemic Sclerosis
Auto-inflammatory Disease
Juvenile Idiopathic Arthritis
Vasculitis
Localized Scleroderma
Juvenile Ankylosing Spondylitis
Juvenile Dermatomyositis
Sarcoid
Idiopathic Uveitis Idiopathic

First Posted Date: 2012-10-02

Last Posted Date: 2015-11-17

Lead Sponsor: Duke University

Target Recruit Count: 9587

Registration Number: NCT01697254

Locations: 🇺🇸
Duke Clinical Research Institute, Durham, North Carolina, United States

Treatment of Acute HIV Infection With Quad Fixed-dose Combination (FDC) Tablet

Phase 3

Completed

Conditions: HIV

Interventions: Drug: (FDC) ELV/COBI/FTC/TDF

First Posted Date: 2012-09-27

Last Posted Date: 2017-04-12

Lead Sponsor: Duke University

Target Recruit Count: 33

Registration Number: NCT01694420

Locations: 🇺🇸
UNC at Chapel Hill, Chapel Hill, North Carolina, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery

Not Applicable

Completed

Conditions: Post Procedural Constipation

Interventions: Drug: Placebo
Drug: MiraLax
Drug: Rescue Laxative

First Posted Date: 2012-09-25

Last Posted Date: 2017-02-15

Lead Sponsor: Duke University

Target Recruit Count: 131

Registration Number: NCT01691742

Locations: 🇺🇸
Duke University, Department of Urogynecology, Durham, North Carolina, United States

Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets

Not Applicable

Completed

Conditions: Hematologic Malignancies

Interventions: Other: Non-neutropenic Diet

First Posted Date: 2012-09-18

Last Posted Date: 2013-05-10

Lead Sponsor: Duke University

Target Recruit Count: 47

Registration Number: NCT01687231

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

Not Applicable

Terminated

Conditions: Heart Failure

Interventions: Device: Biomarker-guided care NT-proBNP
Other: Usual Care

First Posted Date: 2012-09-14

Last Posted Date: 2017-12-12

Lead Sponsor: Duke University

Target Recruit Count: 894

Registration Number: NCT01685840

Locations: 🇺🇸
Drexel University College of Medicine, Philadelphia, Pennsylvania, United States
🇺🇸
AnMed Health Medical Center, Anderson, South Carolina, United States
🇺🇸
University of Texas Southwestern Medical Center Dallas, Dallas, Texas, United States

and more 42 locations

Nitrites, Exercise, and Peripheral Arterial Disease

Phase 2

Completed

Conditions: Peripheral Arterial Disease

Interventions: Drug: Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
Other: Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training

First Posted Date: 2012-09-13

Last Posted Date: 2017-08-29

Lead Sponsor: Duke University

Target Recruit Count: 32

Registration Number: NCT01684930

Locations: 🇺🇸
Duke Diet & Fitness Center, Durham, North Carolina, United States

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