JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Intensive Dysarthria Sessions in Adults and Children With Down Syndrome

Not Applicable

Completed

Conditions: Down Syndrome
Dysarthria

Interventions: Behavioral: Speech sessions

First Posted Date: 2012-09-13

Last Posted Date: 2016-11-23

Lead Sponsor: Duke University

Target Recruit Count: 5

Registration Number: NCT01684670

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression

Phase 4

Completed

Conditions: Major Depressive Disorder Without Psychotic Features

Interventions: Drug: Asenapine 5-20 mg daily
Drug: Placebo 1-4 tablets daily

First Posted Date: 2012-08-21

Last Posted Date: 2015-10-01

Lead Sponsor: Duke University

Target Recruit Count: 46

Registration Number: NCT01670019

Locations: 🇺🇸
Georgia Health Sciences University, Augusta, Georgia, United States
🇺🇸
Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States
🇺🇸
North Carolina Psychiatric Research Center, Raleigh, North Carolina, United States

and more 2 locations

Determination of CRIM Status and Longitudinal Follow-up of Individuals With Pompe Disease

Recruiting

Conditions: Pompe Disease

Interventions: Other: Observational

First Posted Date: 2012-08-15

Last Posted Date: 2024-10-09

Lead Sponsor: Duke University

Target Recruit Count: 400

Registration Number: NCT01665326

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Multisite Prevention of Conduct Problems (Fast Track)

Not Applicable

Active, not recruiting

Conditions: Anti-Social Behavior
Conduct Disorder

Interventions: Behavioral: Fast Track

First Posted Date: 2012-07-31

Last Posted Date: 2024-01-17

Lead Sponsor: Duke University

Target Recruit Count: 891

Registration Number: NCT01653535

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Evaluating a Novel Method of Generalizing Emotion Regulation

Not Applicable

Completed

Conditions: Depression
Difficulties Coping With Negative Emotions
Problems With Emotion Regulation
Anxiety
Psychological Distress
Borderline Personality Disorder

Interventions: Behavioral: Habituation Reminder Training
Behavioral: Habituation Reminder
Behavioral: Habituation

First Posted Date: 2012-07-31

Last Posted Date: 2016-06-23

Lead Sponsor: Duke University

Target Recruit Count: 372

Registration Number: NCT01653548

Locations: 🇺🇸
Duke University Medical Center-Civitan Bldg, Durham, North Carolina, United States

Symptomatic Pulmonary Arterial Hypertension After Mitral Valve Surgery

Completed

Conditions: Pulmonary Hypertension
Mitral Valve Disease

First Posted Date: 2012-07-20

Last Posted Date: 2017-05-03

Lead Sponsor: Duke University

Target Recruit Count: 100

Registration Number: NCT01646541

Locations: 🇺🇸
Northwestern University Medical Center, Chicago, Illinois, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

Phase 3

Completed

Conditions: Dyspnea
Heart Failure

Interventions: Drug: Placebo
Drug: Tolvaptan

First Posted Date: 2012-07-19

Last Posted Date: 2017-04-27

Lead Sponsor: Duke University

Target Recruit Count: 257

Registration Number: NCT01644331

Locations: 🇺🇸
Northeast Georgia Heart Center, Gainesville, Georgia, United States
🇺🇸
University of Colorado at Denver and Health Sciences Center, Aurora, Colorado, United States
🇺🇸
Emory University School of Medicine, Atlanta, Georgia, United States

and more 15 locations

Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia

Phase 1

Completed

Conditions: General Anesthesia

Interventions: Drug: Propofol
Drug: Isoflurane

First Posted Date: 2012-07-13

Last Posted Date: 2015-08-04

Lead Sponsor: Duke University

Target Recruit Count: 105

Registration Number: NCT01640275

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

The Effects of Smoking Withdrawal On Resting State Functional Connectivity

Not Applicable

Withdrawn

Conditions: Smoking

First Posted Date: 2012-07-02

Last Posted Date: 2017-01-31

Lead Sponsor: Duke University

Registration Number: NCT01632384

Locations: 🇺🇸
Duke Health Behavior Neuroscience Research Program, Durham, North Carolina, United States

Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging

Not Applicable

Withdrawn

Conditions: Attention-deficit/Hyperactivity Disorder

First Posted Date: 2012-06-28

Last Posted Date: 2017-01-31

Lead Sponsor: Duke University

Registration Number: NCT01629914

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