JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Health Literacy Project

Not Applicable

Not yet recruiting

Conditions: Epilepsy

Interventions: Other: Health Literacy Educational Session- Comparator
Behavioral: Health Literacy Educational Session

First Posted Date: 2024-10-10

Last Posted Date: 2025-04-16

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06634901

Locations: 🇺🇬
Mbarara Regional Referral Hospital, Mbarara, Uganda
🇺🇬
Mayanja Memorial Hospital, Mbarara, Uganda

Salud, Estrés y Resilencia en Familias/ Health, Stress, and Resilience Among Latino Families in the US

Not Applicable

Not yet recruiting

Conditions: Substance Abuse
Intimate Partner Violence (IPV)
HIV Infections
Depression
Anxiety

Interventions: Behavioral: SER Familia

First Posted Date: 2024-10-04

Last Posted Date: 2025-03-12

Lead Sponsor: Duke University

Target Recruit Count: 400

Registration Number: NCT06627764

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Recruiting

Conditions: Glioblastoma

First Posted Date: 2024-10-03

Last Posted Date: 2025-01-17

Lead Sponsor: Duke University

Target Recruit Count: 200

Registration Number: NCT06625684

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Connectomic Guided DBS for Parkinson's Disease

Not Applicable

Recruiting

Conditions: Parkinson Disease
Tremor
Dyskinesias

Interventions: Device: Cerebellothalamic optimized deep brain stimulation
Device: Pallidothalamic optimized deep brain stimulation
Other: No deep brain stimulation
Device: Usual care deep brain stimulation

First Posted Date: 2024-10-01

Last Posted Date: 2025-04-17

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06618157

Locations: 🇺🇸
Duke Health Center at Morreene Road, Durham, North Carolina, United States

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

Not Applicable

Not yet recruiting

Conditions: Age-Related Macular Degeneration

Interventions: Diagnostic Test: Streetlab VR

First Posted Date: 2024-10-01

Last Posted Date: 2025-05-15

Lead Sponsor: Duke University

Target Recruit Count: 100

Registration Number: NCT06619405

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

GERD in Children With Cystic Fibrosis

Not Applicable

Recruiting

Conditions: GERD in Children
Cystic Fibrosis in Children

Interventions: Other: Discontinuation of GERD therapy

First Posted Date: 2024-09-27

Last Posted Date: 2024-11-25

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06617013

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

PK/PD of Digoxin in Infants With SVHD

Phase 1

Recruiting

Conditions: Single-ventricle
Infant Conditions
Infant, Newborn, Diseases
Infant, Premature, Diseases

Interventions: Drug: PK/PD Model Based Dosing of Digoxin in Infants with Single Ventricle Heart Disease

First Posted Date: 2024-09-26

Last Posted Date: 2024-11-14

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06613477

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States

REVerse Intestinal Metaplasia in the Stomach (REVISE)

Phase 2

Not yet recruiting

Conditions: Gastric Intestinal Metaplasia
Gastric Precancer

Interventions: Drug: Pyrvinium
Drug: Placebo

First Posted Date: 2024-09-19

Last Posted Date: 2025-05-04

Lead Sponsor: Duke University

Target Recruit Count: 32

Registration Number: NCT06590454

Locations: 🇺🇸
Duke Health, Durham, North Carolina, United States

Improving Needs Among Older Adults

Not Applicable

Not yet recruiting

Conditions: Critical Illness
Palliative Care
Older Adults
Informal Caregivers
Care Delivery Model

Interventions: Behavioral: ICUconnect
Other: Usual care

First Posted Date: 2024-09-19

Last Posted Date: 2025-02-18

Lead Sponsor: Duke University

Target Recruit Count: 350

Registration Number: NCT06588556

Locations: 🇺🇸
University of Alabama-Birmingham, Birmingham, Alabama, United States
🇺🇸
Columbia University, New York, New York, United States
🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

and more 1 locations

Community Park-Based Programs for Health Promotion: the Fit2Lead Prospective Cohort Study

Recruiting

Conditions: Anxiety
Wellness, Psychological
Overweight or Obesity
Hypertension
Prehypertension
Low Physical Fitness

Interventions: Behavioral: Fit2Lead Group 1-2

First Posted Date: 2024-09-19

Last Posted Date: 2024-09-19

Lead Sponsor: Duke University

Target Recruit Count: 1000

Registration Number: NCT06596265

Locations: 🇺🇸
Miami-Dade County Parks, Recreation and Open Spaces Department, Miami, Florida, United States

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