JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Rectus Sheath Block for Analgesia After Gynecological Laparotomy

Phase 4

Recruiting

Conditions: Gynecologic Surgical Procedures

Interventions: Procedure: Rectus sheath block
Procedure: Thoracic Epidural Analgesia
Drug: Liposomal bupivacaine
Drug: Bupivacaine-Hydromorphone Cassette
Drug: Bupivacaine Hydrochloride

First Posted Date: 2024-08-28

Last Posted Date: 2024-10-17

Lead Sponsor: Duke University

Target Recruit Count: 90

Registration Number: NCT06575699

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Coping Skills Training for Symptom Management and Daily Steps (Step Up)

Not Applicable

Not yet recruiting

Conditions: Hematopoietic Stem Cell Transplant

Interventions: Behavioral: Step Up
Other: Usual Care Plus (UC+)

First Posted Date: 2024-08-28

Last Posted Date: 2025-04-16

Lead Sponsor: Duke University

Target Recruit Count: 177

Registration Number: NCT06575712

Robotic OCT for ER Anterior Eye Exams

Not Applicable

Recruiting

Conditions: Develop and Test Robotically Assisted Imaging System for the Front of the Eye

Interventions: Device: Robotically Aligned Eye Imaging System

First Posted Date: 2024-08-22

Last Posted Date: 2024-11-21

Lead Sponsor: Duke University

Target Recruit Count: 93

Registration Number: NCT06566339

Locations: 🇺🇸
Duke Eye Center, Durham, North Carolina, United States

Engage Psychosocial Intervention for Cancer Symptoms

Not Applicable

Recruiting

Conditions: Advanced Lung Cancer
Advanced Colorectal Carcinoma
Advanced Colorectal Adenocarcinoma
Advanced Breast Cancer
Advanced Prostate Cancer

Interventions: Behavioral: ENGAGE
Behavioral: Supportive Care

First Posted Date: 2024-08-15

Last Posted Date: 2025-05-04

Lead Sponsor: Duke University

Target Recruit Count: 190

Registration Number: NCT06555588

Locations: 🇺🇸
Duke Cancer Network, Durham, North Carolina, United States

ACHIEVE Pilot Statins for Vascular Protection

Not yet recruiting

Conditions: ASCVD

Interventions: Other: Pharmacist call

First Posted Date: 2024-08-13

Last Posted Date: 2025-03-25

Lead Sponsor: Duke University

Target Recruit Count: 225

Registration Number: NCT06551701

Locations: 🇺🇸
Duke Clinical Research Institute, Durham, North Carolina, United States

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

Not Applicable

Not yet recruiting

Conditions: Epilepsy Intractable

Interventions: Device: Dreem headband

First Posted Date: 2024-08-09

Last Posted Date: 2025-03-19

Lead Sponsor: Duke University

Target Recruit Count: 35

Registration Number: NCT06545643

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Bacterial Decolonization Within Dyads

Not Applicable

Recruiting

Conditions: Bacterial Colonization

Interventions: Drug: Mupirocin
Drug: Chlorhexidine baths

First Posted Date: 2024-08-07

Last Posted Date: 2024-12-19

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06541145

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

Not Applicable

Recruiting

Conditions: Post-traumatic Stress Disorder
Depression
Breath Shortness
Worries; Pain or Disability
Anxiety
Stress

Interventions: Behavioral: Blueprint
Behavioral: Education program

First Posted Date: 2024-08-05

Last Posted Date: 2024-11-22

Lead Sponsor: Duke University

Target Recruit Count: 400

Registration Number: NCT06538246

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

Not Applicable

Not yet recruiting

Conditions: Hematologic Malignancy

Interventions: Behavioral: Nite2Day+

First Posted Date: 2024-08-01

Last Posted Date: 2025-05-09

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06532773

Locations: 🇺🇸
2400 Pratt Street, Durham, North Carolina, United States

Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas

Not Applicable

Not yet recruiting

Conditions: Breast Cancer

Interventions: Behavioral: Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills

First Posted Date: 2024-07-31

Last Posted Date: 2025-05-15

Lead Sponsor: Duke University

Target Recruit Count: 15

Registration Number: NCT06529120

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