DeepMed Research

JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

Phase 3

Not yet recruiting

Conditions: Talaromycosis

Interventions: Drug: Flucytosine (5FC)
Drug: Flucytosine (5FC) placebo pill
Drug: Liposomal Amphotericin B (LAmB)
Drug: Deoxycholate Amphotericin B (DAmB)

First Posted Date: 2024-07-29

Last Posted Date: 2025-03-10

Lead Sponsor: Duke University

Target Recruit Count: 428

Registration Number: NCT06525389

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇻🇳
Bach Mai Hospital, Hanoi, Vietnam
🇻🇳
National Hospital for Tropical Diseases, Hanoi, Vietnam

and more 2 locations

Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery

Not Applicable

Not yet recruiting

Conditions: Trauma
Critical Illness

Interventions: Dietary Supplement: Nutrition Supplements - Fresubin KCAL Drinks

First Posted Date: 2024-07-25

Last Posted Date: 2025-02-28

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06521086

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Ambient Digital Scribes Populating Clinical Notes

Not Applicable

Completed

Conditions: Patient Satisfaction
Clinician Satisfaction

Interventions: Other: Ambient Digital Scribes

First Posted Date: 2024-07-25

Last Posted Date: 2025-02-14

Lead Sponsor: Duke University

Target Recruit Count: 261

Registration Number: NCT06519123

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States

Immunogenicity of Influenza Vaccinations

Phase 4

Active, not recruiting

Conditions: Influenza

Interventions: Biological: Flublok (RIV) or Fluzone (IIV)
Biological: Flucelvax (ccIIV4)

First Posted Date: 2024-07-24

Last Posted Date: 2025-05-21

Lead Sponsor: Duke University

Target Recruit Count: 605

Registration Number: NCT06518577

Locations: 🇺🇸
Valleywise Health Comprehensive Health Center, Phoenix, Arizona, United States
🇺🇸
ASU Biodesign Institute, Tempe, Arizona, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States

and more 4 locations

Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study

Phase 4

Recruiting

Conditions: Safety
Adverse Event Following Immunization
Birth Outcomes

Interventions: Biological: mRNA COVID-19 vaccine
Biological: IIV4 (quadrivalent inactivated influenza vaccine)

First Posted Date: 2024-07-16

Last Posted Date: 2024-10-03

Lead Sponsor: Duke University

Target Recruit Count: 350

Registration Number: NCT06503900

Locations: 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸
Centers for Disease Control and Prevention, Atlanta, Georgia, United States
🇺🇸
Boston Medical Center, Boston, Massachusetts, United States

and more 3 locations

Acute Coronary Syndrome KCMC_1

Not Applicable

Active, not recruiting

Conditions: Hypertension
HIV

Interventions: Behavioral: Community Health Worker (CHW)-delivered Hypertension Management Pilot (CHAMP)
Behavioral: Control of Blood Pressure and Risk Attenuation (COBRA)

First Posted Date: 2024-07-16

Last Posted Date: 2025-05-14

Lead Sponsor: Duke University

Target Recruit Count: 100

Registration Number: NCT06503991

Locations: 🇹🇿
KCMC, Moshi, Tanzania

PrEP (Pre-exposure Prophylaxis) Stigma and Women Ethnodrama Pre-Test Phase

Not Applicable

Recruiting

Conditions: HIV

Interventions: Behavioral: Ethnodrama Intervention

First Posted Date: 2024-07-15

Last Posted Date: 2025-01-28

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT06501885

Locations: 🇰🇪
Impact Research and Development, Kisumu, Kenya

Detecting Traumatic Intracranial Hemorrhage With the InfraScanner 2500™ in Uganda

Not Applicable

Completed

Conditions: Head Trauma
Crushing Skull Injury
Head Injury Major
Injury, Head
Head Injury
Head Injuries, Multiple
Head Trauma, Penetrating
Craniocerebral Injury
Head Trauma,Closed
Trauma, Head

Interventions: Device: InfraScanner 2500™

First Posted Date: 2024-07-08

Last Posted Date: 2025-04-23

Lead Sponsor: Duke University

Target Recruit Count: 180

Registration Number: NCT06491173

Locations: 🇺🇬
Mayanja Memorial Hospital, Mbarara, Uganda
🇺🇬
Mbarara Regional Referral Hospital, Mbarara, Uganda

Single Dose Texas 2017 (H3N2) Challenge Study

Phase 1

Completed

Conditions: Influenza Viral Infections

Interventions: Biological: Sham placebo
Biological: Influenza A/Texas/71/2017 (H3N2)

First Posted Date: 2024-06-26

Last Posted Date: 2025-02-26

Lead Sponsor: Duke University

Target Recruit Count: 33

Registration Number: NCT06476275

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

RIC (Remote Ischemic Conditioning) in Older Individuals

Not Applicable

Conditions: Old Age
Mobility Limitation
Debility

Interventions: Other: Low-intensity resistance exercise training
Other: Remote ischemic conditioning (RIC)

First Posted Date: 2024-06-26

Last Posted Date: 2024-10-18

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT06476288

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

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