JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Study of ALS Reversals 4: LifeTime Exposures

Completed

Conditions: Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Progressive Muscular Atrophy

First Posted Date: 2018-10-16

Last Posted Date: 2023-01-20

Lead Sponsor: Duke University

Target Recruit Count: 25

Registration Number: NCT03706391

Locations: 🇺🇸
Duke ALS Clinic / DUSOM Dept of Neurology / DUHS, Durham, North Carolina, United States

Genicular Nerve Block for Total Knee Arthroplasty

Phase 4

Completed

Conditions: Post-operative Pain

Interventions: Drug: 15mL 0.25% bupivacaine
Procedure: Genicular nerve block
Drug: Saline

First Posted Date: 2018-10-15

Last Posted Date: 2021-04-01

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT03706313

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Testing a Neurocognitive Model of Distancing Using Transcranial Magnetic Stimulation.

Not Applicable

Completed

Conditions: Emotion Regulation
Real Versus Sham Transcranial Magnetic Stimulation (TMS)

Interventions: Device: Sham transcranial magnetic stimulation task
Device: Transcranial magnetic stimulation task

First Posted Date: 2018-10-09

Last Posted Date: 2019-12-17

Lead Sponsor: Duke University

Target Recruit Count: 40

Registration Number: NCT03698591

Locations: 🇺🇸
LaBar Lab, Duke University, Durham, North Carolina, United States

Reach Home and Read

Not Applicable

Terminated

Conditions: Literacy

Interventions: Behavioral: Reach Home and Read Toolkit

First Posted Date: 2018-10-09

Last Posted Date: 2019-10-21

Lead Sponsor: Duke University

Target Recruit Count: 7

Registration Number: NCT03699592

Locations: 🇺🇸
Duke Children's Primary Care, Durham, North Carolina, United States

Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.

Not Applicable

Completed

Conditions: Hypothermia
Rewarming

Interventions: Device: Heated Humidified Breathing Circuit and Forced Air Blanket

First Posted Date: 2018-10-05

Last Posted Date: 2020-07-15

Lead Sponsor: Duke University

Target Recruit Count: 14

Registration Number: NCT03697122

Locations: 🇺🇸
Duke University Hospital, Durham, North Carolina, United States

Blood Flow Restriction Concussion

Not Applicable

Terminated

Conditions: Concussion Post Syndrome

Interventions: Other: Blood Flow Restriction Training with Exercise

First Posted Date: 2018-10-03

Last Posted Date: 2024-11-22

Lead Sponsor: Duke University

Target Recruit Count: 4

Registration Number: NCT03695042

Locations: 🇺🇸
Duke Sports Science Institute, Durham, North Carolina, United States

Developing a Management Approach for Patients With "Late-Onset" Pompe Disease

Active, not recruiting

Conditions: Pompe Disease
Pompe Disease (Late-onset)
GAA Deficiency

Interventions: Other: Observational

First Posted Date: 2018-10-03

Last Posted Date: 2023-10-26

Lead Sponsor: Duke University

Target Recruit Count: 20

Registration Number: NCT03694561

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Comparison of TAP, Anterior QL, or ESP Block for Elective Cesarean Section

Phase 4

Terminated

Conditions: Cesarean Section
Pain, Postoperative

Interventions: Drug: Ropivacaine
Procedure: TAP block
Biological: QL block
Procedure: ESP block

First Posted Date: 2018-10-03

Last Posted Date: 2022-01-12

Lead Sponsor: Duke University

Target Recruit Count: 12

Registration Number: NCT03695172

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

INTERVAL: Ipilimumab and Nivolumab Combination Therapy: A Study of a Supervised or Semi-Supervised Exercise InteRVention or Usual Care With Functional Capacity and Quality of Life Evaluations in Subjects With Advanced or Metastatic RenAL Cell Carcinoma

Not Applicable

Terminated

Conditions: Metastatic Renal Cell Carcinoma

Interventions: Behavioral: Exercise

First Posted Date: 2018-10-02

Last Posted Date: 2019-12-18

Lead Sponsor: Duke University

Target Recruit Count: 2

Registration Number: NCT03692338

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

Sildenafil for Swimming-Induced Pulmonary Edema (SIPE) Prevention

Phase 2

Completed

Conditions: Edema, Pulmonary
Immersion
Diving

Interventions: Drug: Placebo Oral Tablet
Drug: Sildenafil Citrate

First Posted Date: 2018-09-27

Last Posted Date: 2022-11-22

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT03686813

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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