JOHN HOPE FRANKLIN CENTER

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1838-01-01

Employees: 5K

Market Cap: -

Website: http://www.duke.edu

Clinical Trials

Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics

Not Applicable

Withdrawn

Conditions: Alzheimer Dementia
Posttraumatic Stress Disorder
Traumatic Brain Injury

Interventions: Device: MRI
Device: PET
Device: 18F-Florbetapir
Device: Radioligand 18F-AV-1451

First Posted Date: 2018-08-22

Last Posted Date: 2018-10-16

Lead Sponsor: Duke University

Registration Number: NCT03641768

Locations: 🇺🇸
Durham VA, Durham, North Carolina, United States

Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants

Completed

Conditions: Hypoxic-Ischemic Encephalopathy

Interventions: Device: Optical Coherence Tomography

First Posted Date: 2018-08-21

Last Posted Date: 2021-04-08

Lead Sponsor: Duke University

Target Recruit Count: 57

Registration Number: NCT03640494

Locations: 🇺🇸
Duke University Health System, Durham, North Carolina, United States
🇺🇸
University of Utah, Salt Lake City, Utah, United States

Contribution of Urethral Sensory Feedback in Voiding Efficiency

Not Applicable

Completed

Conditions: Urethral Anesthesia

Interventions: Other: Plain aqueous gel
Drug: lidocaine gel

First Posted Date: 2018-08-20

Last Posted Date: 2019-11-14

Lead Sponsor: Duke University

Target Recruit Count: 18

Registration Number: NCT03637582

Locations: 🇺🇸
Duke University Campus, Durham, North Carolina, United States

Deprescribing for Older Dialysis Patients

Completed

Conditions: Kidney Failure, Chronic

Interventions: Behavioral: Deprescribing Intervention

First Posted Date: 2018-08-15

Last Posted Date: 2024-07-10

Lead Sponsor: Duke University

Target Recruit Count: 32

Registration Number: NCT03631290

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Alternate Methodology of Pulse Oximeter Validation

Not Applicable

Suspended

Conditions: Hypoxemia
Desaturation of Blood

Interventions: Device: ROBD Step-Wise desaturation sequence
Device: RespirAct Step-Wise Hypocapnia desaturation sequence
Device: RespirAct Step-Wise Normocapnia desaturation sequence
Device: RespirAct Slope Normocapnia desaturation sequence
Device: RespirAct Slope Hypocapnia desaturation sequence

First Posted Date: 2018-08-14

Last Posted Date: 2022-03-08

Lead Sponsor: Duke University

Target Recruit Count: 30

Registration Number: NCT03628560

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Digital Supportive Care Awareness & Navigation

Not Applicable

Completed

Conditions: Supportive Care

Interventions: Device: D-SCAN

First Posted Date: 2018-08-14

Last Posted Date: 2019-07-18

Lead Sponsor: Duke University

Target Recruit Count: 60

Registration Number: NCT03628794

Locations: 🇺🇸
Duke University Cancer Center, Durham, North Carolina, United States

Cannabis Use and Epigenetic Alterations in Human Male Sperm Cells

Completed

Conditions: Cannabis Use

Interventions: Other: Cannabis use abstinence for 11 weeks

First Posted Date: 2018-08-03

Last Posted Date: 2020-07-07

Lead Sponsor: Duke University

Target Recruit Count: 42

Registration Number: NCT03614637

Locations: 🇺🇸
Duke Child and Family Study Center, Durham, North Carolina, United States

Human Gut Microbiota and Prebiotic Response

Not Applicable

Completed

Conditions: Healthy Gut Microbiota

Interventions: Dietary Supplement: Prebiotic A - inulin
Dietary Supplement: Prebiotic B - galactooligosaccharides(GOS)
Dietary Supplement: Prebiotic C - wheat dextrin

First Posted Date: 2018-07-23

Last Posted Date: 2019-06-03

Lead Sponsor: Duke University

Target Recruit Count: 41

Registration Number: NCT03595306

Locations: 🇺🇸
Duke University, Durham, North Carolina, United States

Adenosine Contrast CorrELations in Evaluating RevAscularizaTION

Phase 4

Completed

Conditions: Percutaneous Coronary Intervention

Interventions: Drug: Iopamidol
Drug: adenosine
Device: Navvus® Catheter
Device: CVi® Contrast Delivery System

First Posted Date: 2018-06-15

Last Posted Date: 2024-07-05

Lead Sponsor: Duke University

Target Recruit Count: 201

Registration Number: NCT03557385

Locations: 🇺🇸
Long Beach VA, Long Beach, California, United States
🇺🇸
Mercy Hospital, Coon Rapids, Minnesota, United States
🇺🇸
Durham VA, Durham, North Carolina, United States

and more 2 locations

Point of Care Testing to Improve Monitoring of LVAD Patients

Not Applicable

Withdrawn

Conditions: Anticoagulation and Thrombosis Point of Care Test (AT-POCT)

Interventions: Device: Anticoagulation and Thrombosis Point of Care Test(AT-POCT)
Device: Duke Central Automated Laboratory (DCAL)

First Posted Date: 2018-06-13

Last Posted Date: 2023-08-09

Lead Sponsor: Duke University

Registration Number: NCT03555552

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States

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