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GlaxoSmithKline

GlaxoSmithKline logo
🇬🇧United Kingdom
Ownership
Public
Established
1929-01-01
Employees
70.2K
Market Cap
$90B
Website
http://www.gsk.com
Introduction

GSK Plc is a healthcare company, which engages in the research, development, and manufacture of pharmaceutical medicines, vaccines, and consumer healthcare products. It operates through the Commercial Operations, and Research and Development segments. The Commercial Operations segment has three product groups of specialty medicines, vaccines, and general medicines. The company was founded in 1715 and is headquartered in Middlesex, the United Kingdom.

Study to Assess the Immunological Long-term Persistence of Antibodies (Abs) 2 Years After GlaxoSmithKline (GSK) Meningococcal ABCWY Vaccination in the V102_15 (NCT02212457) and Response to a Booster in Adolescents

Phase 2
Completed
Conditions
Infections, Meningococcal
Interventions
Biological: Meningococcal ABCWY Vaccine
Biological: Meningococcal B Recombinant vaccine
First Posted Date
2016-10-27
Last Posted Date
2019-08-20
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
604
Registration Number
NCT02946385
Locations
🇵🇱

GSK Investigational Site, Wroclaw, Poland

Pharmacokinetics of Single and Repeat Oral Doses of Trametinib in Chinese Subjects With Solid Tumours

Phase 1
Withdrawn
Conditions
Cancer
Interventions
First Posted Date
2016-10-20
Last Posted Date
2018-09-14
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT02939846

A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive

Not Applicable
Completed
Conditions
Denture Retention
Interventions
Device: Test Product 1
Other: Negative Control
Device: Test Product 2
Device: Reference Product
First Posted Date
2016-10-19
Last Posted Date
2018-05-23
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
25
Registration Number
NCT02937870
Locations
🇺🇸

GSK Investigational Site, Bloomfield, New Jersey, United States

To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population

Not Applicable
Completed
Conditions
Gingivitis
Interventions
Other: Sodium monofluorophosphate
Other: Stannous fluoride
First Posted Date
2016-10-18
Last Posted Date
2019-06-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
128
Registration Number
NCT02937636
Locations
🇨🇳

GSK Investigational Site, Shanghai, China

To Evaluate the Efficacy of an Experimental Dissolvable Strip in Rapidly Relieving Dentinal Hypersensitivity (DH)

Not Applicable
Completed
Conditions
Dentin Sensitivity
Interventions
Device: Dissolvable polymer strip containing Novamin (calcium sodium phosphosilicate)
First Posted Date
2016-10-18
Last Posted Date
2018-01-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
126
Registration Number
NCT02937623
Locations
🇺🇸

GSK Investigational Site, Las Vegas, Nevada, United States

Safety, Clinical Activity, Pharmacokinetics (PK) and Pharmacodynamics Study of GSK2879552, Alone or With Azacitidine, in Subjects With High Risk Myelodysplastic Syndromes (MDS)

Phase 1
Terminated
Conditions
Myelodysplastic Syndrome
Myelodysplastic Syndromes
Interventions
First Posted Date
2016-10-11
Last Posted Date
2019-05-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
7
Registration Number
NCT02929498
Locations
🇪🇸

GSK Investigational Site, Valencia, Spain

Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress

Not Applicable
Completed
Conditions
Denture Retention
Interventions
Device: Experimental Denture Adhesive
Device: Reference (Marketed) Denture Adhesive
First Posted Date
2016-10-10
Last Posted Date
2018-08-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
83
Registration Number
NCT02928380
Locations
🇺🇸

GSK Investigational Site, Fort Wayne, Indiana, United States

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Subjects

Phase 1
Completed
Conditions
Lupus Erythematosus, Cutaneous
Interventions
Drug: GSK2646264 1%
Drug: Placebo
First Posted Date
2016-10-07
Last Posted Date
2021-04-08
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
11
Registration Number
NCT02927457
Locations
🇩🇪

GSK Investigational Site, Berlin, Germany

Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza

Phase 2
Terminated
Conditions
Virus Diseases
Interventions
First Posted Date
2016-10-07
Last Posted Date
2020-11-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
10
Registration Number
NCT02927431
Locations
🇸🇪

GSK Investigational Site, Lund, Sweden

A Study to Evaluate Safety, Reactogenicity and Immunogenicity of GSK Biologicals' RSV Investigational Vaccine Based on Viral Proteins Encoded by Chimpanzee-derived Adenovector (ChAd155-RSV) (GSK3389245A) in RSV-seropositive Infants

Phase 1
Completed
Conditions
Respiratory Syncytial Virus Infections
Interventions
Drug: Placebo
Biological: RSV (GSK3389245A) low dose formulation vaccine
Biological: RSV (GSK3389245A) middle dose formulation vaccine
Biological: RSV (GSK3389245A) high dose formulation vaccine
First Posted Date
2016-10-07
Last Posted Date
2021-10-28
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
107
Registration Number
NCT02927873
Locations
🇨🇳

GSK Investigational Site, Taoyuan, Taiwan

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