MedPath

Arcus Biosciences

Arcus Biosciences logo
🇺🇸United States
Ownership
Public
Established
2015-01-01
Employees
577
Market Cap
-
Website
http://www.arcusbio.com
Introduction

Arcus Biosciences, Inc. engages in the development and commercialization of immunotherapies. It competes in the segments of the pharmaceutical, biotechnology and other related markets that develop immunotherapies for the treatment of cancer. The company was founded by Terry J. Rosen and Juan Carlos Jaen in 2015 and is headquartered in Hayward, CA.

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

Phase 1
Recruiting
Conditions
Healthy Participants
Interventions
First Posted Date
2025-04-09
Last Posted Date
2025-05-18
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
14
Registration Number
NCT06919991
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Phase 3
Recruiting
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
First Posted Date
2024-09-23
Last Posted Date
2025-04-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
610
Registration Number
NCT06608927
Locations
🇫🇷

Gustave Roussy, Villejuif, France

🇩🇪

Krankenhaus Nordwest, Frankfurt am Main, Germany

🇮🇹

Ospedale di Cremona, Cremona, Italy

and more 80 locations

A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies

Phase 1
Recruiting
Conditions
Advanced Cancer
Interventions
First Posted Date
2023-11-07
Last Posted Date
2025-05-08
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
91
Registration Number
NCT06120075
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai/ The Tisch Cancer Center, New York, New York, United States

🇺🇸

START - South Texas Accelerated Research Therapeutics, LLC., San Antonio, Texas, United States

🇺🇸

Sarah Cannon Research Institute, Denver, Colorado, United States

and more 4 locations

A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers

Phase 1
Completed
Conditions
Cancer
Interventions
Drug: Placebo
First Posted Date
2023-08-22
Last Posted Date
2024-08-28
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
32
Registration Number
NCT06004921
Locations
🇬🇧

Quotient Sciences - Nottingham, Nottingham, United Kingdom

A Relative Bioavailability Study and Food Effect Study of AB521 in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2023-08-21
Last Posted Date
2024-10-17
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
24
Registration Number
NCT05999513
Locations
🇺🇸

Celerion, Inc., Lincoln, Nebraska, United States

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Phase 1
Recruiting
Conditions
Bladder Cancer
Advanced Malignancies
Head and Neck Squamous Cell Carcinoma (HNSCC)
Advanced Cancer
Esophageal Cancer
Gastric Cancer
Non-Small Cell Lung Cancer (NSCLC)
Ovarian Cancer
Renal Cell Carcinoma (RCC)
Triple Negative Breast Cancer (TNBC)
Interventions
First Posted Date
2023-06-06
Last Posted Date
2025-04-29
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
87
Registration Number
NCT05891171
Locations
🇨🇳

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, Taiwan

🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇺🇸

Ronald Reagan UCLA Medical Center, Santa Monica, California, United States

and more 17 locations

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Phase 3
Active, not recruiting
Conditions
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Interventions
First Posted Date
2022-10-05
Last Posted Date
2025-02-14
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
1040
Registration Number
NCT05568095
Locations
🇺🇸

UCLA Ronald Reagan Med Ctr, Santa Monica, California, United States

🇺🇸

Smillow Cancer Hosp, New Haven, Connecticut, United States

🇺🇸

Regions Hospital, Saint Louis Park, Minnesota, United States

and more 199 locations

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Phase 1
Recruiting
Conditions
Solid Tumors
Clear Cell Renal Cell Carcinoma
Interventions
First Posted Date
2022-09-10
Last Posted Date
2025-04-27
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
302
Registration Number
NCT05536141
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

University of California at San Diego, San Diego, California, United States

🇺🇸

Medical Oncology Associates Summit Cancer Centers, Spokane, Washington, United States

and more 25 locations

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: [14C]-etrumadenant
First Posted Date
2022-06-09
Last Posted Date
2024-05-24
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
8
Registration Number
NCT05411146
Locations
🇳🇱

PRA Health Sciences (PRA) - Early Development Services (EDS), Groningen, NZ, Netherlands

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Phase 2
Active, not recruiting
Conditions
Gastrointestinal Tract Malignancies
Interventions
First Posted Date
2022-04-15
Last Posted Date
2025-04-23
Lead Sponsor
Arcus Biosciences, Inc.
Target Recruit Count
333
Registration Number
NCT05329766
Locations
🇫🇷

Institut Bergonié _ Bordeaux, Bordeaux, France

🇫🇷

CHU de Brest_Brest, Brest, France

🇫🇷

Centre Baclesse - CAEN, Caen Cedex 5, France

and more 46 locations
© Copyright 2025. All Rights Reserved by MedPath