Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Biomarkers in Tissue Samples From Young Patients With Liver Cancer

Completed

Conditions: Childhood Hepatoblastoma
Stage I Childhood Liver Cancer
Stage III Childhood Liver Cancer
Stage IV Childhood Liver Cancer
Stage II Childhood Liver Cancer

Interventions: Genetic: RNA analysis
Genetic: gene expression analysis
Genetic: microarray analysis
Genetic: nucleic acid sequencing
Other: diagnostic laboratory biomarker analysis

First Posted Date: 2011-04-18

Last Posted Date: 2016-05-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 99

Registration Number: NCT01336881

Locations: 🇺🇸
Children's Oncology Group, Monrovia, California, United States

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

Phase 2

Completed

Conditions: Recurrent Neuroblastoma

Interventions: Biological: hu14.18-IL2 fusion protein
Drug: isotretinoin
Biological: sargramostim
Other: laboratory biomarker analysis

First Posted Date: 2011-04-13

Last Posted Date: 2019-10-21

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 52

Registration Number: NCT01334515

Locations: 🇨🇦
Hospital for Sick Children, Toronto, Ontario, Canada
🇺🇸
Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States
🇺🇸
Natalie W Bryant Cancer Center, Tulsa, Oklahoma, United States

and more 73 locations

Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia

Completed

Conditions: Leukemia

First Posted Date: 2011-03-23

Last Posted Date: 2016-05-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 97

Registration Number: NCT01321385

Biomarkers in Blood and Tumor Tissue Samples From Patients With Wilms Tumor

Completed

Conditions: Renal Failure
Kidney Cancer

First Posted Date: 2011-03-14

Last Posted Date: 2016-05-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 20

Registration Number: NCT01314391

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

Phase 3

Completed

Conditions: Acute Myeloid Leukemia
Adult Acute Monoblastic Leukemia
Adult Acute Monocytic Leukemia
Adult Acute Myeloid Leukemia in Remission
Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With Maturation
Adult Acute Myeloid Leukemia With Minimal Differentiation
Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11
Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1
Adult Acute Myeloid Leukemia With t(9;11)(p22.3;q23.3); MLLT3-KMT2A

Interventions: Drug: Caspofungin Acetate
Drug: Fluconazole
Other: Laboratory Biomarker Analysis

First Posted Date: 2011-03-03

Last Posted Date: 2021-03-30

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 517

Registration Number: NCT01307579

Locations: 🇺🇸
Valley Children's Hospital, Madera, California, United States
🇺🇸
Children's Healthcare of Atlanta - Egleston, Atlanta, Georgia, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

and more 176 locations

Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

Phase 3

Completed

Conditions: Chronic Eosinophilic Leukemia
Chronic Neutrophilic Leukemia
Disseminated Neuroblastoma
Previously Treated Myelodysplastic Syndromes
Recurrent Childhood Acute Myeloid Leukemia
Recurrent Childhood Rhabdomyosarcoma
Recurrent Malignant Testicular Germ Cell Tumor
Recurrent/Refractory Childhood Hodgkin Lymphoma
Unspecified Childhood Solid Tumor, Protocol Specific
Childhood Acute Lymphoblastic Leukemia in Remission

Interventions: Other: placebo
Drug: supersaturated calcium phosphate rinse
Other: questionnaire administration
Procedure: quality-of-life assessment

First Posted Date: 2011-02-28

Last Posted Date: 2019-09-17

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 226

Registration Number: NCT01305200

Locations: 🇺🇸
Lurie Children's Hospital-Chicago, Chicago, Illinois, United States
🇺🇸
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States
🇺🇸
Miami Children's Hospital, Miami, Florida, United States

and more 32 locations

Biomarkers in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia

Completed

Conditions: Leukemia

First Posted Date: 2011-02-17

Last Posted Date: 2016-05-19

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 20

Registration Number: NCT01298414

Biomarker Study in Bone Marrow Samples From Patients With T-Cell Acute Lymphoblastic Leukemia

Completed

Conditions: Leukemia

First Posted Date: 2011-02-14

Last Posted Date: 2016-05-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 135

Registration Number: NCT01295476

Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia

Completed

Conditions: Leukemia

First Posted Date: 2011-02-04

Last Posted Date: 2016-05-18

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 9

Registration Number: NCT01290107

Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma

Phase 1

Completed

Conditions: Brain and Central Nervous System Tumors
Lymphoma
Lymphoproliferative Disorder
Small Intestine Cancer
Unspecified Childhood Solid Tumor, Protocol Specific

Interventions: Drug: imetelstat sodium
Other: laboratory biomarker analysis
Other: pharmacological study

First Posted Date: 2011-01-10

Last Posted Date: 2014-01-30

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 34

Registration Number: NCT01273090

Locations: 🇨🇦
Hospital for Sick Children, Toronto, Ontario, Canada
🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States
🇺🇸
Knight Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States

and more 20 locations

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