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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
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🇺🇸
United States
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Clinical Trials
Related News
A Study of JNJ-54767414 (HuMax CD38) (Anti-CD38 Monoclonal Antibody) in Combination With Backbone Treatments for the Treatment of Patients With Multiple Myeloma
Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
Drug: Daratumumab
Drug: Velcade
Drug: Pomalidomide
Drug: Dexamethasone
Drug: Melphalan
Drug: Thalidomide
Drug: Diphenhydramine
Drug: Prednisone
Drug: Acetaminophen
Drug: Carfilzomib
Drug: Montelukast
Drug: Lenalidomide
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First Posted Date
2013-12-03
Last Posted Date
2025-04-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
240
Registration Number
NCT01998971
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A Study of the Effects of Canagliflozin (JNJ-28431754) on Renal Endpoints in Adult Participants With Type 2 Diabetes Mellitus
Phase 4
Completed
Conditions
Diabetes Mellitus, Type 2
Albuminuria
Interventions
Drug: Canagliflozin, 100 mg
Drug: Placebo
Drug: Canagliflozin, 300 mg
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First Posted Date
2013-11-21
Last Posted Date
2018-12-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
5813
Registration Number
NCT01989754
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A Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis
Phase 2
Completed
Conditions
Colitis, Ulcerative
Interventions
Biological: Golimumab
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First Posted Date
2013-11-20
Last Posted Date
2017-01-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
103
Registration Number
NCT01988961
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An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD
Phase 2
Completed
Conditions
Multiple Myeloma
Interventions
Drug: Daratumumab 16 mg/kg (Part 1)
Drug: Daratumumab 8 mg/kg (Part 1)
Drug: Methylprednisolone
Drug: Daratumumab (Part 2)
Drug: Acetaminophen
Drug: Diphenhydramine
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First Posted Date
2013-11-15
Last Posted Date
2018-06-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
124
Registration Number
NCT01985126
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A Study to Assess the Pharmacokinetics of Intranasally Administered Esketamine in Healthy Japanese and Caucasian Volunteers
Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Esketamine
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First Posted Date
2013-11-08
Last Posted Date
2014-01-28
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
29
Registration Number
NCT01980303
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A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease
Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: JNJ-54861911 10 mg
Drug: JNJ-54861911 50 mg
Drug: Placebo
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First Posted Date
2013-11-07
Last Posted Date
2015-06-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
45
Registration Number
NCT01978548
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A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma
Phase 3
Completed
Conditions
Lymphoma
Interventions
Drug: Bendamustine
Drug: Rituximab
Drug: Cyclophosphamide
Drug: Doxorubicin
Drug: Vincristine
Drug: Prednisone
Drug: Placebo
Drug: PCI-32765 (Ibrutinib)
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First Posted Date
2013-11-01
Last Posted Date
2025-05-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
403
Registration Number
NCT01974440
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A Study of PCI-32765 (Ibrutinib) Versus Rituximab in Relapsed or Refractory Chronic Leukemia/Lymphoma
Phase 3
Completed
Conditions
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Interventions
Drug: Ibrutinib
Drug: Rituximab
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First Posted Date
2013-10-31
Last Posted Date
2018-07-24
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
160
Registration Number
NCT01973387
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A Study to Investigate the Absorption, Metabolism, and Excretion of JNJ-38518168 After a Single Oral Dose in Healthy Male Participants.
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-38518168
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First Posted Date
2013-10-25
Last Posted Date
2013-10-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
6
Registration Number
NCT01970020
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A Pharmacokinetic Study in Healthy Participants to Assess the Pharmacokinetics and Safety of a Supratherapeutic Dose of PCI-32765 (Ibrutinib) Capsule and Solution Formulations Administered With Food
Phase 1
Completed
Conditions
Healthy Volunteer
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First Posted Date
2013-10-25
Last Posted Date
2014-02-13
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
8
Registration Number
NCT01969266
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