EUCTR2005-001670-27-GB进行中（未招募）不适用
Reversibility of cerebrovascular endothelial dysfunction in diabetes: the role of allopurinol.
Greater Glasgow NHS Health Board / University of Glasgow co-sponsorship0 个研究点目标入组 24 人开始时间: 2005年10月17日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Male
入选标准
- •Type II diabetes of less than 5 years' duration treated with diet, metformin, thiazolidinediones or a combination of above
- •Age > 40 years
- •Normal full Bruce protocol exercise tolerance test
- •Favourable temporal bony window
- •Stable glycaemic control (HbA1c < 9.0%)
- •Stable cholesterol (total cholesterol < 7.5
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •>70% extra-cranial internal carotid artery stenosis
- •Known coronary arterial disease
- •Significant co-morbidity
- •Contra-indication to or indication for administration of allopurinol
- •Concurrent azathioprine or 6-mercaptopurine therapy
- •Insulin or sulphonylurea therapy
- •Serum creatinine concentration greater than 250 micromoles per litre
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