NL-OMON33743已完成不适用
Effects of a low-fat vs a high-fat diet on lipid accumulation in liver, skeletal muscle and heart in overweight man - Diet and lipid accumulation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Age 18-65 years
- •BMI 25-35 kg/m2
- •Sedentary
- •Stable dietary habits
- •Not wanting to be informed about a conincedence finding.
排除标准
- •Current use of medication that is known to interfere with the results of the study.
- •Consuming more than 20 g of alcohol per day (± 2 units)
- •Serum-γ-glutamyltranspeptidase level > 70 IU/L
- •A history of cardiovascular disease like congestive heart failure or acute myocardial infarction
- •Plasma triacylglycerol > 4.5 mmol/L
- •Familial hypercholesterolemia
- •A history of liver disease
- •Unstable body weight (weight gain or loss > 3 kg in the past three months)
- •Abuse of drugs
- •Participation in another biomedical study within 1 month prior to the screening visit
- •Impossible or difficult venipuncture during screening
- •a fasting glucose above 7.0 mmol/L
- •a contraindication to MRI scanning. These contraindications include patients with the following devices:
- •o Central nervous system aneurysm clips;
- •o Implanted neural stimulator;
- •o Implanted cardiac pacemaker or defibrillator;
- •o Cochlear implant;
- •o Ocular foreign body (e.g. metal shavings);
- •o Insulin pump;
- •o Metal shrapnel or bullet;
- •o Or metal containing corpora aliena in the eye of brains
研究者
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