CTRI/2023/05/052530尚未招募1 期
Randomised comparative clinical study of effects of dexmetomidine infusion vs midazolam infusion on inflammatory biomarkers in patients with sepsis requring mechanical ventilation
DIKSHA CHOUDHARY0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •In sepsis (patient fulfilling SIRS criteria of sepsis).
- •Patient on mechanical ventilation.
- •Patient having sequential organ failure assessment (SOFA) score of 2 or more.
排除标准
- •1.Patients with history of severe cardiac or pulmonary disease, poorly controlled hypertension.
- •2.Known hypersensitivity to study drugs or using any drug that modifies pain perception.
- •3.Refusal to participate
- •4.Have unpaced second or third degree heart block
- •5.Have uncontrolled hypotension
- •6.Have acute cerebrovascular conditions
- •7.Concurrently using other alpha-2 agonists, eg, clonidine
- •8.Cautions for the following patients who are: -
- •a.Are at risk of exaggerated cardiovascular response, e.g., hypovolaemia
- •b.Have spinal cord injury
- •c.Have severe left ventricular systolic dysfunction
- •d.Are pregnant
- •e.Breast-feeding
- •f.Have seizures disorder
研究者
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