CTRI/2024/02/062836尚未招募1/2 期
To study and compare the effect of preoperative nebulized Magnesium sulphate versus Lignocaine in reducing the incidence of post-operative pharyngo-laryngeal complications in patients undergoing surgery under general anaesthesia with cuffed Endotracheal tube - A prospective triple blind randomised control trial
Supriya1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年2月28日最近更新:
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To evaluate & compare the effectiveness of nebulized Magnesium sulfate & Lignocaine in:
研究概览
简要总结
We will be nebulizing patients with Magnesium sulfate 250mg and Lignocaine 100 mg over 15 minutes and then follow up patients for developing pharyngolaryngeal complications
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA class I-II BMI 18.5-29.9 Undergoing elective surgeries requiring general anaesthesia with cuffed ETT of duration 60-120 minutes.
排除标准
- •Patients refusal for participation in study,hemodynamically unstable pt,history of hypersensitivity to drug used,history of active or recent URTI(last 6 weeks),trauma during intubation,patients on analgesics or steroids.
结局指标
主要结局
To evaluate & compare the effectiveness of nebulized Magnesium sulfate & Lignocaine in:
时间窗: 2 hours,6 hours,12 hours, 24 hours, 48 hours
a.Extubation quality score using 5 points extubation quality score.
时间窗: 2 hours,6 hours,12 hours, 24 hours, 48 hours
b.Post extubation airway related adverse effects like cough,sore throat,hoarseness.
时间窗: 2 hours,6 hours,12 hours, 24 hours, 48 hours
次要结局
- 1.To access the hemodynamic parameter during surgery & extubation.(2.To access the airway dynamics during surgery & extubation.)
研究者
研究点 (1)
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