The Influence of Extracorporeal Circulation During Cardiac Surgery on Optic Nerve Sheath Diameter
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Ultrasound measuring of optic nerve sheath diameter baseline
研究概览
简要总结
The purpose of this study is to assess the influence of extracorporeal circulation during cardiac surgery on the optic nerve sheath diameter (ONSD) after the surgery.
详细描述
ONSD will be measured before and 1 hour after the surgery and in the morning of day 1 after the surgery. Fluid balance and lactate will be measured too. PONV will be assessed. Patients will be evaluated with MoCA test on the day before surgery and on the day 3 after the surgery for cognitive disfunction.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •heart surgery with use of cardiopulmonary bypass
排除标准
- •pregnancy and lactation
- •neurologic disorders
- •hyperthyroidism
- •optic nerve disorders
结局指标
主要结局
Ultrasound measuring of optic nerve sheath diameter baseline
时间窗: Before start of surgery
Baseline optic nerve sheath diameter measurement before start of surgery with a linear ultrasound probe (Scan) in coronal and axial plane
Ultrasound measuring of optic nerve sheath diameter end of surgery
时间窗: 1 hour after the end of surgery
Optic nerve sheath diameter measurement 1 hour after the end of surgery with a linear ultrasound probe in coronal and axial plane
Ultrasound measuring of optic nerve sheath diameter day 1
时间窗: day 1 after the surgery
Optic nerve sheath diameter measurement in the morning on day 1 after the surgery with a linear ultrasound probe in coronal and axial plane
次要结局
- postoperative cognitive disfunction measured with the MoCA test(on the day before surgery, on day 3 after the surgery)
- postoperative nausea and vomiting (PONV)(during the first 24 hours after surgery)