Comparison of intra operative intravenous dexmedetomidine versus fentanyl for attenuating hemodynamic response in laparoscopie cholecystectomy randomized interventional study in the department of anaesthesiology sms medical college and attached group of hospitals
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- To determine the hemodynamic variation from baseline in both the groups in terms
研究概览
简要总结
Our aim is to compare intra operative intravenous Dexmedetomidine versus Fentanyl
for attenuating hemodynamic response in laparoscopic cholecystectomy by monitoring various parameters
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA Grade I & II BMI: 18.5 to 25 Patients bodyb weight 40-70 kgs Undergoing elective laproscopic cholecystectomy Patients willing to give consent.
排除标准
- •Patients allergic to the study drugs Patients with anticipated difficult airway and laryngoscopytime more than 30 seconds Patients on beta blocker.
结局指标
主要结局
To determine the hemodynamic variation from baseline in both the groups in terms
时间窗: 0 BASE line | 10 minutes after the study drug | After inj. Of induction drug | Immediately After intubation | 1min after intubation | 2min after intubation | 5min after intubation | Immediately after pneumoperitoneum | 1min | 5min | 15min | 30min | 60 min | 5 min after release of pneumoperitoneum | Immediately post extubation | 1 min | 2 min | 5 min | 10 min
of difference in mean HR at different time intervals.
时间窗: 0 BASE line | 10 minutes after the study drug | After inj. Of induction drug | Immediately After intubation | 1min after intubation | 2min after intubation | 5min after intubation | Immediately after pneumoperitoneum | 1min | 5min | 15min | 30min | 60 min | 5 min after release of pneumoperitoneum | Immediately post extubation | 1 min | 2 min | 5 min | 10 min
次要结局
- TO DETERMINE CHANGE IN SBP DBP ETCO2 serum cortisol in response to pneumoperitonium(10 min before surgery to 5 min post extubation)
研究者
Dr ChandraShekhar Chatterjee
sms medical college