Comparison of Volume Controlled Ventilation and Pressure Controlled Ventilation in Terms of Respiratory Mechanics in Laparoscopic Bariatric Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- Partial oxygen pressure
研究概览
简要总结
The purpose of this study is to compare volume controlled-ventilation (VCV) and pressure-controlled ventilation (PCV) in terms of pulmonary gas exchange, respiratory mechanics and arterial blood gas values in patients undergoing laparoscopic bariatric surgery.
详细描述
Today, morbid obesity has become a global problem. It is not clear which mechanical ventilation mode will be used in bariatric surgery, which is one of the treatment options of these patients. VCV is the most commonly used mode to ventilate anesthetized patients. However, especially in obese patients, high airway pressures and hypoxia may occur due to increased intrapulmonary shunts. Therefore, we aimed to investigate the potential of PCV strategy to improve pulmonary gas exchange, respiratory mechanics and arterial blood gas values according to VCV in patients undergoing bariatric surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years or above,
- •ASA II patients
- •BMI > 40 kg / m2
- •No serious comorbidity.
排除标准
- •Unstable patients during the operation
- •The requirement for mechanical ventilation in the postoperative period.
研究组 & 干预措施
volume-controlled ventilation group
During the operation, necessary interventions were made by following the algorithm. Hemodynamic and mechanical ventilation parameters of patients were recorded 5 minutes after induction, 30 minutes after pneumoperitoneum and at the end of surgery and were performed arterial blood gas analysis.
干预措施: volume-controlled ventilation (Procedure)
pressure-controlled ventilation group
During the operation, necessary interventions were made by following the algorithm. Hemodynamic and mechanical ventilation parameters of patients were recorded 5 minutes after induction, 30 minutes after pneumoperitoneum and at the end of surgery and were performed arterial blood gas analysis.
干预措施: pressure-controlled ventilation (Procedure)
结局指标
主要结局
Partial oxygen pressure
时间窗: through surgery completion, an average of 90 minutes
Assessed through surgery completion, an average of 90 minutes by using arterial blood gas
次要结局
- Peak airway pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
- Dynamic compliance(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
- Inspired oxygen pressure / Fractional oxygen ratio(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
- Alveolar-arterial oxygen gradient pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
- Partial carbon dioxide pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)
- Partial carbon dioxide pressure - end-tidal carbon dioxide pressure(5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes)