Prolonged weaning and diaphragmatic ultrasound

• Conditions: Z99.1; J96.9; Dependence on respirator; Respiratory failure, unspecified

• Registration Number: DRKS00020937
• Lead Sponsor: Klinik für Operative Intensivmedizin und Intermediate care, Universitätsklinikum RWTH Aachen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-23
• Study Completion: 2021-04-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. admission to the interdisciplinary weaning ward WEA1 for weaning from mechanical ventilation from an acute intensive care unit
2. invasive ventilation via endotracheal tube or tracheal cannula on admission
3. expected duration of treatment at least 5 days

Exclusion Criteria

1. age <18 years
2. pregnancy
3. admission from an outpatient ventilation facility to the weaning ward
4. presence of pre-existing neuromuscular diseases
5. presence of pareses of the diaphragm
6. presence of rib fractures in the examination area
7. presence of surgical wounds in the examination area

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in diaphragmatic thickness, diaphragmatic excursion and fractional thickening during prolonged weaning

Secondary Outcome Measures

Name	Time	Method
1. correlation between diaphragmatic thickness, diaphragmatic excursion and fractional thickening with the spontaneous breathing time achieved<br><br>2. change in the thickness of the quadriceps femoris muscle during prolonged weaning