Prefrontal cortex in aging and effect of aquatic therapy-from ANS and executive function perspective (PART I)

Phase 2

Recruiting

• Conditions: Healthy young and old adultsMild cognitive impairment (MCI); Prefrontal cortex; Autonomic nervous system; Executive function; cognitive impairment

• Registration Number: TCTR20180817005
• Lead Sponsor: ational Health Research Institute, Taiwan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-17
• Study Completion: 2021-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 135

Inclusion Criteria

(1) young adults age between 20 and 30 y/o
(2) older adults age between 65 and 80 y/o
(3) Mini mental status examination (MMSE) > 24 points
(4) Montreal cognitive assessment (MoCA) > 26 points as healthy and < 26 as MCI
(5) Walk independently (without assistive devices) for at least 10 m

Exclusion Criteria

(1) Unstable medical conditions
(2) MMSE < 24
(3) Neurological, cardiac disease, or learning disability
(4) Ongoing regular aquatic exercise program
(5) Contraindication for exercise and hydrotherapy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
executive function It will be assessed after enrollment Stroop Color and Word Test,executive function It will be assessed after enrollment Trail Making Test A, B,autonomic nervous control It will be assessed after enrollment heart rate variability,prefrontal cortex activity It will be assessed after enrollment function near-infrared spectroscopy (fNIRS)

Secondary Outcome Measures

Name	Time	Method
working memory It will be assessed after enrollment Digit Span Test