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Clinical Trials/NCT01478217
NCT01478217
Completed
Not Applicable

Positive End-expiratory Pressure Induced Lung Recruitment -Comparison Between Ultrasonographic Assessment and Lower Inflection Point Assessment on the Pressure -Volume Loop

Sisters of Mercy University Hospital1 site in 1 country17 target enrollmentOctober 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Respiratory Distress Syndrome
Sponsor
Sisters of Mercy University Hospital
Enrollment
17
Locations
1
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.

Detailed Description

Sedated and sometimes temporary relaxed patients with ALI/ARDS on mechanical ventilation in semirecumbent position are included. Lower inflection point on pressure volume loop on ventilator Draeger Evita 4 with low continuous flow on volume controlled ventilation is measured with zero PEEP. Transthoracic lung ultrasound with linear probe is proceed on both hemithoraces when mechanical ventilation based on measured PEEP is started. We compare if real lung recruitment seen by ultrasound is the same as predicted by lower inflection point. The procedure is a part of routine everyday respiratory monitoring in our unit.

Registry
clinicaltrials.gov
Start Date
October 2009
End Date
November 2011
Last Updated
14 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Sisters of Mercy University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Bojan Rode

dr.med.

Sisters of Mercy University Hospital

Eligibility Criteria

Inclusion Criteria

  • patients with diffuse ALI/ARDS on mechanical ventilation with visible lower inflection point on dynamic P-V loops

Exclusion Criteria

  • preexisting parenchymal or pleural lung disease

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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