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Correlation between nitric oxide and urodynamics in men with bladder outlet obstructio

Not Applicable
Completed
Conditions
Diseases of The genitoruinary system
Registration Number
KCT0003042
Lead Sponsor
The Catholic University of Korea, Bucheon St. Mary's Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
46
Inclusion Criteria

1) men aged 50-75 years old who were scheduled for surgical treatment for BPH
2) underwent a urodynamic study before surgery and agreed to donate bladder tissue

Exclusion Criteria

1) prostate cancer diagnosed previously or after surgery for BPH
2) a history of prostatic, bladder and/or urethral surgery
3) a history of acute urinary tract infection within 1 month
4) interstitial cystitis, and bladder cancer
5) patients who indwelling bladder catheter for more than 1 month

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
correlation between expression of eNOS, iNOS, nNOS in urothelitum and urodynamic parameters
Secondary Outcome Measures
NameTimeMethod
difference of expression of nNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group;difference of expression of eNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group;difference of expression of iNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group
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