Determination of Protein Requirements in Healthy Pregnant Women Using Indicator Amino Acid Oxidation Technique
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- 13 Carbon dioxide production
研究概览
简要总结
Protein is an essential part of our diet. It is used to build muscle and body tissue, send signals throughout our body and to support the immune system. Dietary protein is even more crucial during pregnancy as it is needed for healthy growth and development of the baby. There is very minimal data available on how much additional protein is required during pregnancy. Current recommendations are based on older techniques such as nitrogen balance studies of non-pregnant adults and minimally based on pregnancy specific data. There is no scientific information regarding the amount of protein needed during different stages of pregnancy.
The investigators hypothesize that the current recommendations of protein intake during pregnancy are underestimated.
The goal of this study is to measure protein requirement in healthy pregnant women (19-35y)using a more quick and modern technique called the indicator amino acid oxidation technique (IAAO).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 19 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Healthy pregnant women
- •Singleton pregnancy
- •Maternal age 19-35y
- •In good health (free of chronic/acute disease,full range of physical mobility)
- •Healthy pre-pregnancy body mass index
排除标准
- •not pregnant
- •Pregnant with more than one child
- •Singleton pregnancy outside the age range of 19-35y
- •Not in good health or have a metabolic, neurological, genetic, or immune disorder, including gestational diabetes or anemia
- •smoke or consume alcohol during their pregnancy
- •classified as underweight (<18.5 kg/m2), overweight (25-30 kg/m2) or obese (>30 kg/m2)
- •allergic to eggs and egg protein
- •severe nausea/vomiting throughout their pregnancy
研究组 & 干预措施
Protein Intake
Dietary supplement:Protein intake
干预措施: Protein Intake (Dietary Supplement)
结局指标
主要结局
13 Carbon dioxide production
时间窗: 8 hours (1 study day)
Urine and breath samples will be collected during the study to measure the rate of oxidation of tracer in expired breath and flux by enrichment in urine.
次要结局
未报告次要终点
研究者
Rajavel Elango, PhD
Principle Investigator
University of British Columbia